node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AKJ00654.1 | AKJ02604.1 | AA314_02280 | AA314_04230 | 2-Keto-3-deoxy-D-manno-octulosonate-8-phosphate synthase; Belongs to the KdsA family. | Lipid IVA 3-deoxy-D-manno-octulosonic acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | 0.851 |
AKJ00654.1 | AKJ06945.1 | AA314_02280 | AA314_08571 | 2-Keto-3-deoxy-D-manno-octulosonate-8-phosphate synthase; Belongs to the KdsA family. | Arabinose 5-phosphate isomerase; Belongs to the SIS family. GutQ/KpsF subfamily. | 0.988 |
AKJ00654.1 | kdsB | AA314_02280 | AA314_02284 | 2-Keto-3-deoxy-D-manno-octulosonate-8-phosphate synthase; Belongs to the KdsA family. | 3-deoxy-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. | 0.867 |
AKJ00654.1 | lpxA | AA314_02280 | AA314_04212 | 2-Keto-3-deoxy-D-manno-octulosonate-8-phosphate synthase; Belongs to the KdsA family. | Acyl-[acyl-carrier-protein]--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.791 |
AKJ00654.1 | lpxB | AA314_02280 | AA314_04218 | 2-Keto-3-deoxy-D-manno-octulosonate-8-phosphate synthase; Belongs to the KdsA family. | Lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.836 |
AKJ00654.1 | lpxC | AA314_02280 | AA314_03903 | 2-Keto-3-deoxy-D-manno-octulosonate-8-phosphate synthase; Belongs to the KdsA family. | UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. | 0.840 |
AKJ00654.1 | lpxD | AA314_02280 | AA314_04210 | 2-Keto-3-deoxy-D-manno-octulosonate-8-phosphate synthase; Belongs to the KdsA family. | UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. | 0.811 |
AKJ00654.1 | lpxK | AA314_02280 | AA314_04232 | 2-Keto-3-deoxy-D-manno-octulosonate-8-phosphate synthase; Belongs to the KdsA family. | Tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). | 0.854 |
AKJ02604.1 | AKJ00654.1 | AA314_04230 | AA314_02280 | Lipid IVA 3-deoxy-D-manno-octulosonic acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | 2-Keto-3-deoxy-D-manno-octulosonate-8-phosphate synthase; Belongs to the KdsA family. | 0.851 |
AKJ02604.1 | AKJ06945.1 | AA314_04230 | AA314_08571 | Lipid IVA 3-deoxy-D-manno-octulosonic acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | Arabinose 5-phosphate isomerase; Belongs to the SIS family. GutQ/KpsF subfamily. | 0.874 |
AKJ02604.1 | kdsB | AA314_04230 | AA314_02284 | Lipid IVA 3-deoxy-D-manno-octulosonic acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | 3-deoxy-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. | 0.985 |
AKJ02604.1 | lpxA | AA314_04230 | AA314_04212 | Lipid IVA 3-deoxy-D-manno-octulosonic acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | Acyl-[acyl-carrier-protein]--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.844 |
AKJ02604.1 | lpxB | AA314_04230 | AA314_04218 | Lipid IVA 3-deoxy-D-manno-octulosonic acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | Lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.861 |
AKJ02604.1 | lpxC | AA314_04230 | AA314_03903 | Lipid IVA 3-deoxy-D-manno-octulosonic acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. | 0.859 |
AKJ02604.1 | lpxD | AA314_04230 | AA314_04210 | Lipid IVA 3-deoxy-D-manno-octulosonic acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. | 0.846 |
AKJ02604.1 | lpxK | AA314_04230 | AA314_04232 | Lipid IVA 3-deoxy-D-manno-octulosonic acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | Tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). | 0.999 |
AKJ06945.1 | AKJ00654.1 | AA314_08571 | AA314_02280 | Arabinose 5-phosphate isomerase; Belongs to the SIS family. GutQ/KpsF subfamily. | 2-Keto-3-deoxy-D-manno-octulosonate-8-phosphate synthase; Belongs to the KdsA family. | 0.988 |
AKJ06945.1 | AKJ02604.1 | AA314_08571 | AA314_04230 | Arabinose 5-phosphate isomerase; Belongs to the SIS family. GutQ/KpsF subfamily. | Lipid IVA 3-deoxy-D-manno-octulosonic acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | 0.874 |
AKJ06945.1 | kdsB | AA314_08571 | AA314_02284 | Arabinose 5-phosphate isomerase; Belongs to the SIS family. GutQ/KpsF subfamily. | 3-deoxy-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. | 0.875 |
AKJ06945.1 | lpxA | AA314_08571 | AA314_04212 | Arabinose 5-phosphate isomerase; Belongs to the SIS family. GutQ/KpsF subfamily. | Acyl-[acyl-carrier-protein]--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.866 |