node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AKJ01443.1 | AKJ02997.1 | AA314_03069 | AA314_04623 | TsaC protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. | TsaE protein, required for threonylcarbamoyladenosine t(6)A37 formation in tRNA. | 0.672 |
AKJ01443.1 | AKJ05611.1 | AA314_03069 | AA314_07237 | TsaC protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. | TsaB protein, required for threonylcarbamoyladenosine. | 0.622 |
AKJ01443.1 | tsaD | AA314_03069 | AA314_07904 | TsaC protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. | TsaD/Kae1/Qri7 protein, required for threonylcarbamoyladenosine t(6)A37 formation in tRNA; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | 0.652 |
AKJ02997.1 | AKJ01443.1 | AA314_04623 | AA314_03069 | TsaE protein, required for threonylcarbamoyladenosine t(6)A37 formation in tRNA. | TsaC protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. | 0.672 |
AKJ02997.1 | AKJ04034.1 | AA314_04623 | AA314_05660 | TsaE protein, required for threonylcarbamoyladenosine t(6)A37 formation in tRNA. | Hypothetical protein; Belongs to the SUA5 family. | 0.622 |
AKJ02997.1 | AKJ05324.1 | AA314_04623 | AA314_06950 | TsaE protein, required for threonylcarbamoyladenosine t(6)A37 formation in tRNA. | Dihydrofolate synthase; Belongs to the folylpolyglutamate synthase family. | 0.606 |
AKJ02997.1 | AKJ05611.1 | AA314_04623 | AA314_07237 | TsaE protein, required for threonylcarbamoyladenosine t(6)A37 formation in tRNA. | TsaB protein, required for threonylcarbamoyladenosine. | 0.968 |
AKJ02997.1 | acpS | AA314_04623 | AA314_04621 | TsaE protein, required for threonylcarbamoyladenosine t(6)A37 formation in tRNA. | Holo-[acyl-carrier protein] synthase; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family. | 0.801 |
AKJ02997.1 | miaA | AA314_04623 | AA314_05347 | TsaE protein, required for threonylcarbamoyladenosine t(6)A37 formation in tRNA. | tRNA dimethylallyltransferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. | 0.702 |
AKJ02997.1 | nnrE | AA314_04623 | AA314_04622 | TsaE protein, required for threonylcarbamoyladenosine t(6)A37 formation in tRNA. | NAD(P)HX epimerase / NAD(P)HX dehydratase; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow t [...] | 0.948 |
AKJ02997.1 | pdxJ | AA314_04623 | AA314_04620 | TsaE protein, required for threonylcarbamoyladenosine t(6)A37 formation in tRNA. | Pyridoxine 5'-phosphate synthase; Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino- 2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate. | 0.801 |
AKJ02997.1 | tilS | AA314_04623 | AA314_04615 | TsaE protein, required for threonylcarbamoyladenosine t(6)A37 formation in tRNA. | tRNA(Ile)-lysidine synthetase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family. | 0.623 |
AKJ02997.1 | tsaD | AA314_04623 | AA314_07904 | TsaE protein, required for threonylcarbamoyladenosine t(6)A37 formation in tRNA. | TsaD/Kae1/Qri7 protein, required for threonylcarbamoyladenosine t(6)A37 formation in tRNA; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | 0.920 |
AKJ04034.1 | AKJ02997.1 | AA314_05660 | AA314_04623 | Hypothetical protein; Belongs to the SUA5 family. | TsaE protein, required for threonylcarbamoyladenosine t(6)A37 formation in tRNA. | 0.622 |
AKJ04034.1 | AKJ05611.1 | AA314_05660 | AA314_07237 | Hypothetical protein; Belongs to the SUA5 family. | TsaB protein, required for threonylcarbamoyladenosine. | 0.622 |
AKJ04034.1 | tsaD | AA314_05660 | AA314_07904 | Hypothetical protein; Belongs to the SUA5 family. | TsaD/Kae1/Qri7 protein, required for threonylcarbamoyladenosine t(6)A37 formation in tRNA; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | 0.736 |
AKJ05324.1 | AKJ02997.1 | AA314_06950 | AA314_04623 | Dihydrofolate synthase; Belongs to the folylpolyglutamate synthase family. | TsaE protein, required for threonylcarbamoyladenosine t(6)A37 formation in tRNA. | 0.606 |
AKJ05324.1 | miaA | AA314_06950 | AA314_05347 | Dihydrofolate synthase; Belongs to the folylpolyglutamate synthase family. | tRNA dimethylallyltransferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. | 0.502 |
AKJ05324.1 | tilS | AA314_06950 | AA314_04615 | Dihydrofolate synthase; Belongs to the folylpolyglutamate synthase family. | tRNA(Ile)-lysidine synthetase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family. | 0.443 |
AKJ05611.1 | AKJ01443.1 | AA314_07237 | AA314_03069 | TsaB protein, required for threonylcarbamoyladenosine. | TsaC protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. | 0.622 |