node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AKJ02363.1 | menB | AA314_03989 | AA314_04837 | Putative nucleoside-diphosphate-sugar epimerase. | Naphthoate synthase; Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2- naphthoyl-CoA (DHNA-CoA); Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily. | 0.588 |
AKJ02363.1 | menD | AA314_03989 | AA314_05026 | Putative nucleoside-diphosphate-sugar epimerase. | 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylic-acid synthase; Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2- succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC). Belongs to the TPP enzyme family. MenD subfamily. | 0.415 |
AKJ02784.1 | AKJ03398.1 | AA314_04410 | AA314_05024 | Isochorismate synthase. | Menaquinone-specific isochorismate synthase. | 0.936 |
AKJ02784.1 | menA | AA314_04410 | AA314_05028 | Isochorismate synthase. | 1,4-dihydroxy-2-naphthoate polyprenyltransferase; Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK); Belongs to the MenA family. Type 1 subfamily. | 0.477 |
AKJ02784.1 | menB | AA314_04410 | AA314_04837 | Isochorismate synthase. | Naphthoate synthase; Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2- naphthoyl-CoA (DHNA-CoA); Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily. | 0.638 |
AKJ02784.1 | menD | AA314_04410 | AA314_05026 | Isochorismate synthase. | 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylic-acid synthase; Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2- succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC). Belongs to the TPP enzyme family. MenD subfamily. | 0.994 |
AKJ02784.1 | menH | AA314_04410 | AA314_05027 | Isochorismate synthase. | 2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylate synthase; Catalyzes a proton abstraction reaction that results in 2,5- elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6- hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). | 0.669 |
AKJ03398.1 | AKJ02784.1 | AA314_05024 | AA314_04410 | Menaquinone-specific isochorismate synthase. | Isochorismate synthase. | 0.936 |
AKJ03398.1 | menA | AA314_05024 | AA314_05028 | Menaquinone-specific isochorismate synthase. | 1,4-dihydroxy-2-naphthoate polyprenyltransferase; Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK); Belongs to the MenA family. Type 1 subfamily. | 0.916 |
AKJ03398.1 | menB | AA314_05024 | AA314_04837 | Menaquinone-specific isochorismate synthase. | Naphthoate synthase; Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2- naphthoyl-CoA (DHNA-CoA); Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily. | 0.774 |
AKJ03398.1 | menC | AA314_05024 | AA314_05029 | Menaquinone-specific isochorismate synthase. | O-succinylbenzoate synthase; Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB). | 0.806 |
AKJ03398.1 | menD | AA314_05024 | AA314_05026 | Menaquinone-specific isochorismate synthase. | 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylic-acid synthase; Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2- succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC). Belongs to the TPP enzyme family. MenD subfamily. | 0.992 |
AKJ03398.1 | menE | AA314_05024 | AA314_05030 | Menaquinone-specific isochorismate synthase. | O-succinylbenzoic acid--CoA ligase; Converts 2-succinylbenzoate (OSB) to 2-succinylbenzoyl-CoA (OSB-CoA); Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily. | 0.733 |
AKJ03398.1 | menH | AA314_05024 | AA314_05027 | Menaquinone-specific isochorismate synthase. | 2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylate synthase; Catalyzes a proton abstraction reaction that results in 2,5- elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6- hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). | 0.913 |
AKJ04805.1 | AKJ06740.1 | AA314_06431 | AA314_08366 | Enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family. | Enoyl-CoA hydratase. | 0.636 |
AKJ04805.1 | menB | AA314_06431 | AA314_04837 | Enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family. | Naphthoate synthase; Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2- naphthoyl-CoA (DHNA-CoA); Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily. | 0.687 |
AKJ04805.1 | menE | AA314_06431 | AA314_05030 | Enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family. | O-succinylbenzoic acid--CoA ligase; Converts 2-succinylbenzoate (OSB) to 2-succinylbenzoyl-CoA (OSB-CoA); Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily. | 0.406 |
AKJ06740.1 | AKJ04805.1 | AA314_08366 | AA314_06431 | Enoyl-CoA hydratase. | Enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family. | 0.636 |
AKJ06740.1 | menB | AA314_08366 | AA314_04837 | Enoyl-CoA hydratase. | Naphthoate synthase; Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2- naphthoyl-CoA (DHNA-CoA); Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily. | 0.569 |
menA | AKJ02784.1 | AA314_05028 | AA314_04410 | 1,4-dihydroxy-2-naphthoate polyprenyltransferase; Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK); Belongs to the MenA family. Type 1 subfamily. | Isochorismate synthase. | 0.477 |