node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AKJ03326.1 | htpX-2 | AA314_04952 | AA314_04953 | Integral membrane protein TerC. | Peptidase M48, Ste24p precursor; Belongs to the peptidase M48B family. | 0.557 |
AKJ05124.1 | htpX-2 | AA314_06750 | AA314_04953 | Integral membrane protein; Belongs to the BI1 family. | Peptidase M48, Ste24p precursor; Belongs to the peptidase M48B family. | 0.538 |
AKJ06323.1 | grpE | AA314_07949 | AA314_06266 | FxsA protein. | Heat shock protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP- [...] | 0.455 |
AKJ06323.1 | grpE-2 | AA314_07949 | AA314_09392 | FxsA protein. | Heat shock protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP- [...] | 0.539 |
AKJ06323.1 | htpX-2 | AA314_07949 | AA314_04953 | FxsA protein. | Peptidase M48, Ste24p precursor; Belongs to the peptidase M48B family. | 0.479 |
ftsH | htpX-2 | AA314_04617 | AA314_04953 | Cell division protein FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | Peptidase M48, Ste24p precursor; Belongs to the peptidase M48B family. | 0.612 |
ftsH-2 | htpX-2 | AA314_06085 | AA314_04953 | Cell division protein FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | Peptidase M48, Ste24p precursor; Belongs to the peptidase M48B family. | 0.531 |
ftsH-3 | grpE | AA314_06268 | AA314_06266 | Cell division protein FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | Heat shock protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP- [...] | 0.649 |
ftsH-3 | htpX-2 | AA314_06268 | AA314_04953 | Cell division protein FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | Peptidase M48, Ste24p precursor; Belongs to the peptidase M48B family. | 0.612 |
grpE | AKJ06323.1 | AA314_06266 | AA314_07949 | Heat shock protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP- [...] | FxsA protein. | 0.455 |
grpE | ftsH-3 | AA314_06266 | AA314_06268 | Heat shock protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP- [...] | Cell division protein FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | 0.649 |
grpE | htpX-2 | AA314_06266 | AA314_04953 | Heat shock protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP- [...] | Peptidase M48, Ste24p precursor; Belongs to the peptidase M48B family. | 0.499 |
grpE-2 | AKJ06323.1 | AA314_09392 | AA314_07949 | Heat shock protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP- [...] | FxsA protein. | 0.539 |
grpE-2 | htpX-2 | AA314_09392 | AA314_04953 | Heat shock protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP- [...] | Peptidase M48, Ste24p precursor; Belongs to the peptidase M48B family. | 0.499 |
htpX-2 | AKJ03326.1 | AA314_04953 | AA314_04952 | Peptidase M48, Ste24p precursor; Belongs to the peptidase M48B family. | Integral membrane protein TerC. | 0.557 |
htpX-2 | AKJ05124.1 | AA314_04953 | AA314_06750 | Peptidase M48, Ste24p precursor; Belongs to the peptidase M48B family. | Integral membrane protein; Belongs to the BI1 family. | 0.538 |
htpX-2 | AKJ06323.1 | AA314_04953 | AA314_07949 | Peptidase M48, Ste24p precursor; Belongs to the peptidase M48B family. | FxsA protein. | 0.479 |
htpX-2 | ftsH | AA314_04953 | AA314_04617 | Peptidase M48, Ste24p precursor; Belongs to the peptidase M48B family. | Cell division protein FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | 0.612 |
htpX-2 | ftsH-2 | AA314_04953 | AA314_06085 | Peptidase M48, Ste24p precursor; Belongs to the peptidase M48B family. | Cell division protein FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | 0.531 |
htpX-2 | ftsH-3 | AA314_04953 | AA314_06268 | Peptidase M48, Ste24p precursor; Belongs to the peptidase M48B family. | Cell division protein FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | 0.612 |