STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
icmFB12 binding domain / kinase domain / Methylmalonyl-CoA mutase; Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly. (1156 aa)    
Predicted Functional Partners:
AKJ00694.1
Methylmalonyl-CoA mutase.
 
 
0.999
AKJ00695.1
Methylmalonyl-CoA mutase.
 
 
0.999
AKJ00696.1
Putative periplasmic protein kinase ArgK.
 
  
0.874
AKJ03741.1
Hydroxymethylglutaryl-CoA lyase.
     
 0.794
AKJ03740.1
Methyltransferase type 11.
       0.782
AKJ04445.1
4-hydroxybutyrate coenzyme A transferase.
  
  
 0.729
AKJ05191.1
Acetyl-CoA hydrolase.
  
  
 0.729
AKJ02048.1
Enoyl-CoA hydratase.
 
  
 0.704
AKJ07111.1
Periplasmic binding protein.
 
  
 0.667
AKJ07625.1
Vitamin B12 ABC transporter, B12-binding component BtuF.
 
  
 0.609
Your Current Organism:
Archangium gephyra
NCBI taxonomy Id: 48
Other names: A. gephyra, ATCC 25201, Chondrococcus cerebriformis, Chondromyces serpens, DSM 2261, Myxococcus cerebriformis
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