node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
aroE | nadD | Minf_2478 | Minf_1361 | Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | Nicotinic acid mononucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.708 |
cinA | nadC | Minf_1558 | Minf_2412 | CinA protein; Belongs to the CinA family. | Nicotinate-nucleotide pyrophosphorylase; Belongs to the NadC/ModD family. | 0.950 |
cinA | nadD | Minf_1558 | Minf_1361 | CinA protein; Belongs to the CinA family. | Nicotinic acid mononucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.964 |
cinA | nadE | Minf_1558 | Minf_0725 | CinA protein; Belongs to the CinA family. | NAD synthetase and glutamine amidotransferase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.653 |
cinA | pncB | Minf_1558 | Minf_0838 | CinA protein; Belongs to the CinA family. | Nicotinic acid phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | 0.952 |
nadC | cinA | Minf_2412 | Minf_1558 | Nicotinate-nucleotide pyrophosphorylase; Belongs to the NadC/ModD family. | CinA protein; Belongs to the CinA family. | 0.950 |
nadC | nadD | Minf_2412 | Minf_1361 | Nicotinate-nucleotide pyrophosphorylase; Belongs to the NadC/ModD family. | Nicotinic acid mononucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.928 |
nadC | nadE | Minf_2412 | Minf_0725 | Nicotinate-nucleotide pyrophosphorylase; Belongs to the NadC/ModD family. | NAD synthetase and glutamine amidotransferase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.543 |
nadC | pncB | Minf_2412 | Minf_0838 | Nicotinate-nucleotide pyrophosphorylase; Belongs to the NadC/ModD family. | Nicotinic acid phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | 0.940 |
nadD | aroE | Minf_1361 | Minf_2478 | Nicotinic acid mononucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | 0.708 |
nadD | cinA | Minf_1361 | Minf_1558 | Nicotinic acid mononucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | CinA protein; Belongs to the CinA family. | 0.964 |
nadD | nadC | Minf_1361 | Minf_2412 | Nicotinic acid mononucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | Nicotinate-nucleotide pyrophosphorylase; Belongs to the NadC/ModD family. | 0.928 |
nadD | nadE | Minf_1361 | Minf_0725 | Nicotinic acid mononucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | NAD synthetase and glutamine amidotransferase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.955 |
nadD | nadF | Minf_1361 | Minf_2045 | Nicotinic acid mononucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.930 |
nadD | pncB | Minf_1361 | Minf_0838 | Nicotinic acid mononucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | Nicotinic acid phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | 0.939 |
nadD | pntA | Minf_1361 | Minf_1482 | Nicotinic acid mononucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | NAD/NADP transhydrogenase alpha subunit. | 0.902 |
nadD | pntA-2 | Minf_1361 | Minf_1483 | Nicotinic acid mononucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | NAD/NADP transhydrogenase alpha subunit. | 0.902 |
nadD | pntB | Minf_1361 | Minf_1484 | Nicotinic acid mononucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | NAD/NADP transhydrogenase beta subunit; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family. | 0.902 |
nadD | rsfS | Minf_1361 | Minf_1363 | Nicotinic acid mononucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | Uncharacterized conserved protein, Iojap family; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. | 0.779 |
nadE | cinA | Minf_0725 | Minf_1558 | NAD synthetase and glutamine amidotransferase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | CinA protein; Belongs to the CinA family. | 0.653 |