Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
splBDNA repair photolyase. (352 aa)    
Predicted Functional Partners:
lysR-2
Transcriptional regulator, LysR/CysB family; Belongs to the LysR transcriptional regulatory family.
       0.741
lexA
SOS-response transcriptional repressor LexA/UmuD (HTH, RecA-mediated autopeptidase); Belongs to the peptidase S24 family.
     
 0.668
recA
RecA/RadA recombinase; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
      
 0.659
rnhB
Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
     
 0.642
uvrA
Excinuclease ABC subunit A, ATPase; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.
      
 0.627
uvrA-2
Excinuclease ABC subunit A, ATPase; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.
      
 0.627
dinG
Rad3-related DNA helicase.
      
 0.623
uvrD
ATP-dependent DNA helicase UvrD/PcrA.
     
 0.620
Minf_2014
Hypothetical protein.
       0.600
Minf_2015
Transposon IS605 OrfA, integrase-resolvase.
       0.427
Your Current Organism:
Methylacidiphilum infernorum
NCBI taxonomy Id: 481448
Other names: M. infernorum V4, Methylacidiphilum infernorum V4, Methylacidiphilum infernorum str. V4, Methylacidiphilum infernorum strain V4, Verrucomicrobia bacterium V4, Verrucomicrobiae bacterium V4
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