STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pepT_1Peptidase T; Cleaves the N-terminal amino acid of tripeptides. Belongs to the peptidase M20B family. (412 aa)    
Predicted Functional Partners:
gshAB_4
Glutathione biosynthesis bifunctional protein GshAB; Belongs to the glutamate--cysteine ligase type 1 family.
   
 
 0.871
OFA10052.1
Putative GTP cyclohydrolase 1 type 2; Belongs to the GTP cyclohydrolase I type 2/NIF3 family.
  
    0.836
trmK
tRNA (adenine(22)-N(1))-methyltransferase.
  
    0.761
pepN
Aminopeptidase N.
     
 0.645
pepQ
Xaa-Pro dipeptidase.
  
 
 0.628
OFA12848.1
Telomeric repeat-binding factor 2.
   
  0.589
argD
Acetylornithine aminotransferase.
   
  0.589
sigA
RNA polymerase sigma factor SigA; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
  
    0.551
clpB
Chaperone protein ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family.
  
  
 0.537
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
   
 
 0.528
Your Current Organism:
Lactobacillus sunkii
NCBI taxonomy Id: 481719
Other names: DSM 19904, JCM 15039, L. sunkii, Lactobacillus sp. YIT 11161, Lactobacillus sp. YIT 11442, Lactobacillus sp. YIT 11539, Lactobacillus sp. YIT 11549, Lactobacillus sp. YIT 11557, Lactobacillus sp. YIT 11635, Lactobacillus sunkii Watanabe et al. 2009, NRIC 0744, YIT 11161
Server load: low (10%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.