STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gshAB_4Glutathione biosynthesis bifunctional protein GshAB; Belongs to the glutamate--cysteine ligase type 1 family. (510 aa)    
Predicted Functional Partners:
glnA
Glutamine synthetase.
  
 
 0.954
pepN
Aminopeptidase N.
     
 0.925
purQ
Phosphoribosylformylglycinamidine synthase 1; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...]
    
  0.924
gdhA
NAD(P)-specific glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
    
 0.922
metC
Cystathionine beta-lyase.
    
 0.903
metI
Cystathionine gamma-synthase/O-acetylhomoserine (thiol)-lyase.
    
 0.903
gshAB_3
Glutathione biosynthesis bifunctional protein GshAB; Belongs to the glutamate--cysteine ligase type 1 family.
 
  
 
0.885
gshAB_1
Glutathione biosynthesis bifunctional protein GshAB; Belongs to the glutamate--cysteine ligase type 1 family.
 
  
 
0.882
gshAB_2
Glutathione biosynthesis bifunctional protein GshAB; Belongs to the glutamate--cysteine ligase type 1 family.
 
  
 
0.882
pepT_1
Peptidase T; Cleaves the N-terminal amino acid of tripeptides. Belongs to the peptidase M20B family.
   
 
 0.871
Your Current Organism:
Lactobacillus sunkii
NCBI taxonomy Id: 481719
Other names: DSM 19904, JCM 15039, L. sunkii, Lactobacillus sp. YIT 11161, Lactobacillus sp. YIT 11442, Lactobacillus sp. YIT 11539, Lactobacillus sp. YIT 11549, Lactobacillus sp. YIT 11557, Lactobacillus sp. YIT 11635, Lactobacillus sunkii Watanabe et al. 2009, NRIC 0744, YIT 11161
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