OFA09361.1 protein (Lactobacillus sunkii) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

OFA09361.1

Major facilitator superfamily protein. (439 aa)

Predicted Functional Partners:

OFA09362.1

0.891

yjmB_6

0.839

rhaS_2

0.764

OFA13259.1

0.607

cwlO

0.516

OFA10349.1

0.479

OFA12594.1

0.475

OFA09854.1

0.468

OFA09313.1

0.462

Your Current Organism:

Lactobacillus sunkii

NCBI taxonomy Id: 481719
Other names: DSM 19904, JCM 15039, L. sunkii, Lactobacillus sp. YIT 11161, Lactobacillus sp. YIT 11442, Lactobacillus sp. YIT 11539, Lactobacillus sp. YIT 11549, Lactobacillus sp. YIT 11557, Lactobacillus sp. YIT 11635, Lactobacillus sunkii Watanabe et al. 2009, NRIC 0744, YIT 11161

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
OFA09313.1	OFA09361.1	LASUN_25800	LASUN_26280	Hypothetical protein.	Major facilitator superfamily protein.	0.462
OFA09313.1	OFA09362.1	LASUN_25800	LASUN_26290	Hypothetical protein.	Bacterial alpha-L-rhamnosidase.	0.416
OFA09313.1	OFA09854.1	LASUN_25800	LASUN_23360	Hypothetical protein.	Hypothetical protein.	0.412
OFA09313.1	OFA12594.1	LASUN_25800	LASUN_05320	Hypothetical protein.	Hypothetical protein.	0.773
OFA09313.1	OFA13259.1	LASUN_25800	LASUN_02580	Hypothetical protein.	Glycosyl hydrolase family 59.	0.436
OFA09361.1	OFA09313.1	LASUN_26280	LASUN_25800	Major facilitator superfamily protein.	Hypothetical protein.	0.462
OFA09361.1	OFA09362.1	LASUN_26280	LASUN_26290	Major facilitator superfamily protein.	Bacterial alpha-L-rhamnosidase.	0.891
OFA09361.1	OFA09854.1	LASUN_26280	LASUN_23360	Major facilitator superfamily protein.	Hypothetical protein.	0.468
OFA09361.1	OFA10349.1	LASUN_26280	LASUN_19580	Major facilitator superfamily protein.	Acetyltransferase (GNAT) family protein.	0.479
OFA09361.1	OFA12594.1	LASUN_26280	LASUN_05320	Major facilitator superfamily protein.	Hypothetical protein.	0.475
OFA09361.1	OFA13259.1	LASUN_26280	LASUN_02580	Major facilitator superfamily protein.	Glycosyl hydrolase family 59.	0.607
OFA09361.1	cwlO	LASUN_26280	LASUN_10010	Major facilitator superfamily protein.	Peptidoglycan DL-endopeptidase CwlO precursor.	0.516
OFA09361.1	rhaS_2	LASUN_26280	LASUN_26310	Major facilitator superfamily protein.	HTH-type transcriptional activator RhaS.	0.764
OFA09361.1	yjmB_6	LASUN_26280	LASUN_26300	Major facilitator superfamily protein.	Putative symporter YjmB.	0.839
OFA09362.1	OFA09313.1	LASUN_26290	LASUN_25800	Bacterial alpha-L-rhamnosidase.	Hypothetical protein.	0.416
OFA09362.1	OFA09361.1	LASUN_26290	LASUN_26280	Bacterial alpha-L-rhamnosidase.	Major facilitator superfamily protein.	0.891
OFA09362.1	OFA09854.1	LASUN_26290	LASUN_23360	Bacterial alpha-L-rhamnosidase.	Hypothetical protein.	0.703
OFA09362.1	OFA13259.1	LASUN_26290	LASUN_02580	Bacterial alpha-L-rhamnosidase.	Glycosyl hydrolase family 59.	0.837
OFA09362.1	rhaS_2	LASUN_26290	LASUN_26310	Bacterial alpha-L-rhamnosidase.	HTH-type transcriptional activator RhaS.	0.721
OFA09362.1	yjmB_6	LASUN_26290	LASUN_26300	Bacterial alpha-L-rhamnosidase.	Putative symporter YjmB.	0.913

page 1 of 3

Network Stats

number of nodes:

11

number of edges:

27

average node degree:

4.91

avg. local clustering coefficient:

0.786

expected number of edges:

34

PPI enrichment p-value:

0.914

your network does not have significantly more
interactions than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006351

Transcription, DNA-templated

5 of 20

1.87

2.45

3.51e-06

GO:0010467

Gene expression

9 of 208

1.11

1.3

1.46e-06

GO:0009059

Macromolecule biosynthetic process

9 of 232

1.06

1.21

1.88e-06

GO:0031564

Transcription antitermination

2 of 4

2.17

0.98

0.0148

GO:0006353

DNA-templated transcription, termination

2 of 4

2.17

0.98

0.0148

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0003899

DNA-directed 5-3 RNA polymerase activity

3 of 5

2.25

1.7

0.00058

GO:0003735

Structural constituent of ribosome

4 of 55

1.33

1.0

0.0035

GO:0003723

RNA binding

5 of 96

1.19

0.98

0.0015

GO:0003676

Nucleic acid binding

9 of 370

0.86

0.78

0.00012

GO:0019843

rRNA binding

3 of 40

1.34

0.7

0.0297

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0000428

DNA-directed RNA polymerase complex

3 of 6

2.17

1.8

0.00033

GO:0005840

Ribosome

4 of 59

1.3

1.06

0.0018

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:74

Ribonucleoprotein, and Translation regulator activity

11 of 92

1.55

3.38

1.42e-14

CL:77

Ribosome, and Translation regulator activity

9 of 75

1.55

3.02

1.33e-11

CL:99

Ribosome

5 of 37

1.6

2.03

6.66e-06

CL:84

Ribosome

6 of 62

1.46

1.93

1.80e-06

CL:101

rRNA-binding

3 of 23

1.58

1.16

0.0030

(more ...)

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

con03020

RNA polymerase

3 of 4

2.34

2.07

0.00012

con03010

Ribosome

4 of 53

1.35

1.11

0.0015

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0008023

Transcription elongation factor complex

2 of 2

2.47

0.99

0.0157

GOCC:0000428

DNA-directed RNA polymerase complex

4 of 63

1.27

0.77

0.0157

GOCC:0022627

Cytosolic small ribosomal subunit

2 of 11

1.73

0.76

0.0320

GOCC:0005840

Ribosome

3 of 47

1.27

0.71

0.0238

GOCC:0032991

Protein-containing complex

8 of 534

0.65

0.43

0.0157

(more ...)

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0240

DNA-directed RNA polymerase

3 of 7

2.1

1.84

0.00025

KW-0689

Ribosomal protein

5 of 59

1.4

1.37

0.00023

KW-0889

Transcription antitermination

2 of 3

2.29

1.3

0.0037

KW-0806

Transcription termination

2 of 3

2.29

1.3

0.0037

KW-0548

Nucleotidyltransferase

3 of 33

1.43

1.0

0.0052

(more ...)

Protein Domains (SMART)

domain

description

count in network

strength

signal

false discovery rate

SM00322

K homology RNA-binding domain

2 of 3

2.29

1.06

0.0110

Enrichment display settings

Enrichment analysis is still ongoing, please wait ...

Server load: low (20%) [HD]

Permalink

Network

Neighborhood

Databases

Cooccurrence

Textmining

Coexpression

Experiments

Fusion

© STRING Consortium 2024

Credits

Access

Info

About