node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACX62364.1 | ACX63588.1 | GYMC10_0054 | GYMC10_1301 | KEGG: pjd:Pjdr2_0062 hypoxanthine phosphoribosyltransferase; TIGRFAM: hypoxanthine phosphoribosyltransferase; PFAM: phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | PFAM: 5'-Nucleotidase domain protein; metallophosphoesterase; Ig domain protein group 2 domain protein; S-layer domain protein; Ig family protein; SMART: Ig domain protein group 2 domain protein; KEGG: pjd:Pjdr2_0981 Ig domain protein group 2 domain protein. | 0.903 |
ACX62364.1 | ACX63778.1 | GYMC10_0054 | GYMC10_1493 | KEGG: pjd:Pjdr2_0062 hypoxanthine phosphoribosyltransferase; TIGRFAM: hypoxanthine phosphoribosyltransferase; PFAM: phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | Non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.911 |
ACX62364.1 | ACX64420.1 | GYMC10_0054 | GYMC10_2139 | KEGG: pjd:Pjdr2_0062 hypoxanthine phosphoribosyltransferase; TIGRFAM: hypoxanthine phosphoribosyltransferase; PFAM: phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | Purine nucleoside phosphorylase I, inosine and guanosine-specific; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | 0.936 |
ACX62364.1 | apt | GYMC10_0054 | GYMC10_1571 | KEGG: pjd:Pjdr2_0062 hypoxanthine phosphoribosyltransferase; TIGRFAM: hypoxanthine phosphoribosyltransferase; PFAM: phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.927 |
ACX62364.1 | deoD | GYMC10_0054 | GYMC10_5646 | KEGG: pjd:Pjdr2_0062 hypoxanthine phosphoribosyltransferase; TIGRFAM: hypoxanthine phosphoribosyltransferase; PFAM: phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | TIGRFAM: purine nucleoside phosphorylase; PFAM: purine or other phosphorylase family 1; KEGG: bcz:BCZK1344 purine nucleoside phosphorylase. | 0.914 |
ACX62364.1 | deoD-2 | GYMC10_0054 | GYMC10_6244 | KEGG: pjd:Pjdr2_0062 hypoxanthine phosphoribosyltransferase; TIGRFAM: hypoxanthine phosphoribosyltransferase; PFAM: phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | TIGRFAM: purine nucleoside phosphorylase; PFAM: purine or other phosphorylase family 1; KEGG: amt:Amet_4228 purine nucleoside phosphorylase. | 0.914 |
ACX62364.1 | gmk | GYMC10_0054 | GYMC10_1946 | KEGG: pjd:Pjdr2_0062 hypoxanthine phosphoribosyltransferase; TIGRFAM: hypoxanthine phosphoribosyltransferase; PFAM: phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.937 |
ACX62364.1 | guaA | GYMC10_0054 | GYMC10_0905 | KEGG: pjd:Pjdr2_0062 hypoxanthine phosphoribosyltransferase; TIGRFAM: hypoxanthine phosphoribosyltransferase; PFAM: phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | 0.950 |
ACX62364.1 | guaB | GYMC10_0054 | GYMC10_0074 | KEGG: pjd:Pjdr2_0062 hypoxanthine phosphoribosyltransferase; TIGRFAM: hypoxanthine phosphoribosyltransferase; PFAM: phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.952 |
ACX62364.1 | xpt-2 | GYMC10_0054 | GYMC10_4563 | KEGG: pjd:Pjdr2_0062 hypoxanthine phosphoribosyltransferase; TIGRFAM: hypoxanthine phosphoribosyltransferase; PFAM: phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | Xanthine phosphoribosyltransferase; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis. | 0.923 |
ACX63588.1 | ACX62364.1 | GYMC10_1301 | GYMC10_0054 | PFAM: 5'-Nucleotidase domain protein; metallophosphoesterase; Ig domain protein group 2 domain protein; S-layer domain protein; Ig family protein; SMART: Ig domain protein group 2 domain protein; KEGG: pjd:Pjdr2_0981 Ig domain protein group 2 domain protein. | KEGG: pjd:Pjdr2_0062 hypoxanthine phosphoribosyltransferase; TIGRFAM: hypoxanthine phosphoribosyltransferase; PFAM: phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.903 |
ACX63588.1 | ACX63778.1 | GYMC10_1301 | GYMC10_1493 | PFAM: 5'-Nucleotidase domain protein; metallophosphoesterase; Ig domain protein group 2 domain protein; S-layer domain protein; Ig family protein; SMART: Ig domain protein group 2 domain protein; KEGG: pjd:Pjdr2_0981 Ig domain protein group 2 domain protein. | Non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.901 |
ACX63588.1 | ACX64420.1 | GYMC10_1301 | GYMC10_2139 | PFAM: 5'-Nucleotidase domain protein; metallophosphoesterase; Ig domain protein group 2 domain protein; S-layer domain protein; Ig family protein; SMART: Ig domain protein group 2 domain protein; KEGG: pjd:Pjdr2_0981 Ig domain protein group 2 domain protein. | Purine nucleoside phosphorylase I, inosine and guanosine-specific; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | 0.912 |
ACX63588.1 | apt | GYMC10_1301 | GYMC10_1571 | PFAM: 5'-Nucleotidase domain protein; metallophosphoesterase; Ig domain protein group 2 domain protein; S-layer domain protein; Ig family protein; SMART: Ig domain protein group 2 domain protein; KEGG: pjd:Pjdr2_0981 Ig domain protein group 2 domain protein. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.906 |
ACX63588.1 | deoD | GYMC10_1301 | GYMC10_5646 | PFAM: 5'-Nucleotidase domain protein; metallophosphoesterase; Ig domain protein group 2 domain protein; S-layer domain protein; Ig family protein; SMART: Ig domain protein group 2 domain protein; KEGG: pjd:Pjdr2_0981 Ig domain protein group 2 domain protein. | TIGRFAM: purine nucleoside phosphorylase; PFAM: purine or other phosphorylase family 1; KEGG: bcz:BCZK1344 purine nucleoside phosphorylase. | 0.901 |
ACX63588.1 | deoD-2 | GYMC10_1301 | GYMC10_6244 | PFAM: 5'-Nucleotidase domain protein; metallophosphoesterase; Ig domain protein group 2 domain protein; S-layer domain protein; Ig family protein; SMART: Ig domain protein group 2 domain protein; KEGG: pjd:Pjdr2_0981 Ig domain protein group 2 domain protein. | TIGRFAM: purine nucleoside phosphorylase; PFAM: purine or other phosphorylase family 1; KEGG: amt:Amet_4228 purine nucleoside phosphorylase. | 0.901 |
ACX63588.1 | gmk | GYMC10_1301 | GYMC10_1946 | PFAM: 5'-Nucleotidase domain protein; metallophosphoesterase; Ig domain protein group 2 domain protein; S-layer domain protein; Ig family protein; SMART: Ig domain protein group 2 domain protein; KEGG: pjd:Pjdr2_0981 Ig domain protein group 2 domain protein. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.900 |
ACX63588.1 | guaA | GYMC10_1301 | GYMC10_0905 | PFAM: 5'-Nucleotidase domain protein; metallophosphoesterase; Ig domain protein group 2 domain protein; S-layer domain protein; Ig family protein; SMART: Ig domain protein group 2 domain protein; KEGG: pjd:Pjdr2_0981 Ig domain protein group 2 domain protein. | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | 0.917 |
ACX63588.1 | guaB | GYMC10_1301 | GYMC10_0074 | PFAM: 5'-Nucleotidase domain protein; metallophosphoesterase; Ig domain protein group 2 domain protein; S-layer domain protein; Ig family protein; SMART: Ig domain protein group 2 domain protein; KEGG: pjd:Pjdr2_0981 Ig domain protein group 2 domain protein. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.924 |
ACX63588.1 | xpt-2 | GYMC10_1301 | GYMC10_4563 | PFAM: 5'-Nucleotidase domain protein; metallophosphoesterase; Ig domain protein group 2 domain protein; S-layer domain protein; Ig family protein; SMART: Ig domain protein group 2 domain protein; KEGG: pjd:Pjdr2_0981 Ig domain protein group 2 domain protein. | Xanthine phosphoribosyltransferase; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis. | 0.906 |