STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACX68244.1PFAM: biotin/lipoate A/B protein ligase; KEGG: pjd:Pjdr2_5950 biotin/lipoate A/B protein ligase. (285 aa)    
Predicted Functional Partners:
ACX67401.1
KEGG: gwc:GWCH70_1752 lipoyltransferase and lipoate-protein ligase; TIGRFAM: lipoyltransferase and lipoate-protein ligase; PFAM: Lipoate protein ligase-like; biotin/lipoate A/B protein ligase.
 
  
 0.947
lipA
Lipoic acid synthetase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
  
 
 0.929
lipB
Lipoate-protein ligase B; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
   
 0.921
gcvH
Glycine cleavage system H protein; Is also involved in protein lipoylation via its role as an octanoyl/lipoyl carrier protein intermediate; Belongs to the GcvH family.
 
 
 0.862
ACX66310.1
PFAM: HesB/YadR/YfhF-family protein; KEGG: bha:BH2252 hypothetical protein.
  
    0.769
ACX64682.1
TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: pyridine nucleotide-disulphide oxidoreductase dimerisation region; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; glucose-inhibited division protein A; KEGG: pjd:Pjdr2_2653 dihydrolipoamide dehydrogenase.
 
 
 0.704
ACX64681.1
PFAM: catalytic domain of components of various dehydrogenase complexes; biotin/lipoyl attachment domain-containing protein; E3 binding domain protein; KEGG: pjd:Pjdr2_2652 catalytic domain of components of various dehydrogenase complexes.
 
 0.667
ACX64680.1
PFAM: Transketolase central region; Transketolase domain protein; KEGG: pjd:Pjdr2_2651 transketolase central region.
 
 
 0.631
ACX64407.1
PFAM: Transketolase central region; Transketolase domain protein; KEGG: pjd:Pjdr2_2322 transketolase central region.
 
 
 0.606
pdhA
Pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).
 
 
 0.595
Your Current Organism:
Paenibacillus sp. Y412MC10
NCBI taxonomy Id: 481743
Other names: P. sp. Y412MC10
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