Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Score
rsfSIojap protein family; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. (117 aa)    
Predicted Functional Partners:
rplS
50S ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
  
  0.951
EIQ81183.1
Methyltransferase; COG0500 SAM-dependent methyltransferases.
  
  
 0.949
rplT
50S ribosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.
  
 0.947
EIQ81177.1
GTP-binding protein YqeH; COG1161 Predicted GTPases.
  
 
 0.939
rplP
50S ribosomal protein L16; Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs; Belongs to the universal ribosomal protein uL16 family.
  
  0.933
rpmF
COG0333 Ribosomal protein L32; Belongs to the bacterial ribosomal protein bL32 family.
  
 0.933
rpmH
50S ribosomal protein L34; Belongs to the bacterial ribosomal protein bL34 family.
   
 
 0.932
rplU
50S ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.
  
  0.928
rplQ
COG0203 Ribosomal protein L17.
  
 0.926
rplO
50S ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family.
    
  0.923
Your Current Organism:
Streptococcus canis
NCBI taxonomy Id: 482234
Other names: S. canis FSL Z3-227, Streptococcus canis FSL Z3-227, Streptococcus canis str. FSL Z3-227, Streptococcus canis strain FSL Z3-227
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