STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
OPX45895.1Vitamin B12 dependent methionine synthase, activation domain. (215 aa)    
Predicted Functional Partners:
metH_1
Methionine synthase.
 
 
 0.965
yitJ_1
Bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase.
 
 
 0.961
metF
5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.
 
 
 0.868
nifJ
Pyruvate-flavodoxin oxidoreductase.
    
 0.866
yitJ_2
Bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase.
 
 
 0.794
acsC
Corrinoid/iron-sulfur protein large subunit.
   
 0.762
glpE
Thiosulfate sulfurtransferase GlpE.
     
 0.727
metG_1
methionine--tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
    
  0.724
fhs
Formate--tetrahydrofolate ligase; Belongs to the formate--tetrahydrofolate ligase family.
    
 0.663
ahcY
Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
    
 0.663
Your Current Organism:
Ruminiclostridium hungatei
NCBI taxonomy Id: 48256
Other names: ATCC 700212, Clostridium hungatei, Clostridium hungatei Monserrate et al. 2001, DSM 14427, R. hungatei, strain AD
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.