STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
OPX44960.1Putative 2-hydroxyacid dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (317 aa)    
Predicted Functional Partners:
serC
Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine.
  
 0.867
nifJ
Pyruvate-flavodoxin oxidoreductase.
  
 
 0.862
gmhB
D-glycero-alpha-D-manno-heptose-1,7-bisphosphate 7-phosphatase.
   
 0.844
thrZ
threonine--tRNA ligase 2.
   
  0.833
OPX42372.1
Putative 2-hydroxyacid dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
 
  
0.764
rebO
Flavin-dependent L-tryptophan oxidase RebO precursor.
    
 0.746
kdgA
KHG/KDPG aldolase.
    
 0.725
korA_2
2-oxoglutarate oxidoreductase subunit KorA.
  
 
 0.703
cysNC
Bifunctional enzyme CysN/CysC; May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
  
  
 0.695
trpB_2
Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
  
 0.688
Your Current Organism:
Ruminiclostridium hungatei
NCBI taxonomy Id: 48256
Other names: ATCC 700212, Clostridium hungatei, Clostridium hungatei Monserrate et al. 2001, DSM 14427, R. hungatei, strain AD
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