STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hemE_2Uroporphyrinogen decarboxylase; Belongs to the uroporphyrinogen decarboxylase family. (359 aa)    
Predicted Functional Partners:
metH_2
Methionine synthase.
 
 0.961
nasF
uroporphyrinogen-III C-methyltransferase.
  
 
 0.903
hemE_1
Uroporphyrinogen decarboxylase; Belongs to the uroporphyrinogen decarboxylase family.
 
 
 
0.900
cysG
Siroheme synthase.
    
 0.897
OPX42962.1
Hypothetical protein.
  
 
 0.879
metH_3
Methionine synthase.
 
 0.877
mphP
Phenol hydroxylase P5 protein.
 
    0.852
hemC
Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
 
 0.832
nqrF
Na(+)-translocating NADH-quinone reductase subunit F.
 
    0.802
hemZ_1
Oxygen-independent coproporphyrinogen-III oxidase-like protein HemZ.
  
 
 0.798
Your Current Organism:
Ruminiclostridium hungatei
NCBI taxonomy Id: 48256
Other names: ATCC 700212, Clostridium hungatei, Clostridium hungatei Monserrate et al. 2001, DSM 14427, R. hungatei, strain AD
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