STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
glpK_1Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate. (517 aa)    
Predicted Functional Partners:
mec
CysO-cysteine peptidase.
   
 0.980
gmhB
D-glycero-alpha-D-manno-heptose-1,7-bisphosphate 7-phosphatase.
   
 0.837
ftsH_2
ATP-dependent zinc metalloprotease FtsH.
 
 
  0.833
ftsH_3
ATP-dependent zinc metalloprotease FtsH.
   
  0.833
ftsH3
ATP-dependent zinc metalloprotease FtsH 3.
 
 
  0.833
alaS
alanine--tRNA ligase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
   
  0.810
OPX44033.1
Ankyrin repeat protein.
   
 0.803
OPX43361.1
Tetratricopeptide repeat protein.
   
 0.803
plsY
Glycerol-3-phosphate acyltransferase; Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
    
 0.802
OPX44139.1
Hypothetical protein.
   
 0.802
Your Current Organism:
Ruminiclostridium hungatei
NCBI taxonomy Id: 48256
Other names: ATCC 700212, Clostridium hungatei, Clostridium hungatei Monserrate et al. 2001, DSM 14427, R. hungatei, strain AD
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.