STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SDE85224.1Glyoxalase-like domain-containing protein. (125 aa)    
Predicted Functional Partners:
SDE85255.1
Uncharacterized protein, contains GYD domain.
       0.778
guaA
GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
       0.722
SDE85286.1
Endonuclease, Uma2 family (restriction endonuclease fold).
       0.709
SDE85338.1
Probable regulatory domain-containing protein.
       0.695
SDE85367.1
KaiC domain protein, AF_0795 family.
       0.575
luxS
S-ribosylhomocysteine lyase /quorum-sensing autoinducer 2 (AI-2) synthesis protein LuxS; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family.
       0.430
SDE85422.1
Methylthioadenosine nucleosidase; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Belongs to the PNP/UDP phosphorylase family. MtnN subfamily.
       0.430
SDE52791.1
Hydroxyacylglutathione hydrolase.
   
 
  0.426
SDE85446.1
Ribose-phosphate pyrophosphokinase.
       0.413
SDE64485.1
DNA end-protection protein DdrA.
  
     0.412
Your Current Organism:
Thermus arciformis
NCBI taxonomy Id: 482827
Other names: CGMCC 1.6992, JCM 15153, T. arciformis, Thermus arciformis Zhang et al. 2010, Thermus sp. TH91, Thermus sp. TH92, strain TH92
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