STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SDE84800.1Malate synthase; Belongs to the malate synthase family. (520 aa)    
Predicted Functional Partners:
SDE80785.1
Isocitrate lyase.
 
 0.999
SDE84754.1
Glycolate oxidase FAD binding subunit.
  
 
 0.951
mdh
Malate dehydrogenase (NAD); Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family.
   
 0.949
SDF16978.1
Citrate synthase; Belongs to the citrate synthase family.
   
 0.949
SDE62353.1
Transcriptional regulator, IclR family.
  
 0.946
SDE84731.1
Glycolate oxidase iron-sulfur subunit.
  
 
 0.946
SDE84777.1
Glycolate oxidase.
  
 
 0.943
SDE58198.1
acetyl-CoA synthetase.
   
 0.925
SDE62326.1
Acetyl-coenzyme A synthetase.
   
 0.925
acsA
Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
   
 0.925
Your Current Organism:
Thermus arciformis
NCBI taxonomy Id: 482827
Other names: CGMCC 1.6992, JCM 15153, T. arciformis, Thermus arciformis Zhang et al. 2010, Thermus sp. TH91, Thermus sp. TH92, strain TH92
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