STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A168MP51ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (988 aa)    
Predicted Functional Partners:
A0A163MTB8
DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.
  
 0.991
A0A163JIV7
DNA repair protein RAD51 homolog; Required both for recombination and for the repair of DNA damage caused by X-rays; Belongs to the RecA family. RAD51 subfamily.
  
 0.990
A0A163MTR5
TPR_REGION domain-containing protein.
  
 0.990
A0A168N5Y5
Uncharacterized protein.
   
 0.987
A0A163MP03
ERCC4 domain-containing protein.
   
 0.986
A0A163LQH2
ERCC4 domain-containing protein.
   
 0.985
A0A168SZW0
Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.
  
 0.985
A0A163K350
RMI1_N domain-containing protein.
   
 0.984
A0A168LID3
Uncharacterized protein; Belongs to the PI3/PI4-kinase family.
   
 0.984
A0A163K6S5
DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.
  
 0.982
Your Current Organism:
Absidia glauca
NCBI taxonomy Id: 4829
Other names: A. glauca, CBS 101.08, MUCL 10044
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