STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
thiMPutative hydroxyethylthiazole kinase; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family. (277 aa)    
Predicted Functional Partners:
thiE
Thiamine-phosphate diphosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.
 
 0.999
thiD
KEGG: cac:CAC3095 2.0e-69 thiK; phosphomethylpyrimidine kinase K00877:K00941; Psort location: Cytoplasmic, score: 8.96.
 
 0.997
EEC58820.1
Putative thiamine-phosphate diphosphorylase; KEGG: cpe:CPE1599 1.3e-21 thiE; thiamin phosphate pyrophosphorylase K00788; Psort location: Cytoplasmic, score: 8.96.
 
 
 0.991
thiW
Protein ThiW; KEGG: mma:MM0701 0.0034 vacuolar-type H+-pyrophosphatase K01507; Psort location: CytoplasmicMembrane, score: 10.00.
 
     0.922
thiC
Thiamine biosynthesis protein ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family.
  
 
 0.864
thiS
Thiamine biosynthesis protein ThiS.
  
 
  0.820
EEC57210.1
Hypothetical protein.
     
 0.640
EEC57160.1
KEGG: cbu:CBU_0587 3.3e-07 glpE protein, putative K02439.
  
  
 0.495
dxs
1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily.
      
 0.491
EEC57130.1
KEGG: cpf:CPF_1988 8.1e-27 thiamine pyrophosphokinase K00949; Psort location: Cytoplasmic, score: 8.96.
     
 0.470
Your Current Organism:
Bacteroides pectinophilus
NCBI taxonomy Id: 483218
Other names: Bacteroides pectinophilus ATCC 43243, [. pectinophilus ATCC 43243, [Bacteroides] pectinophilus ATCC 43243, [Bacteroides] pectinophilus str. ATCC 43243, [Bacteroides] pectinophilus strain ATCC 43243
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