Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
AJF05708.1Nickel-responsive regulator; Transcriptional regulator; Belongs to the transcriptional regulatory CopG/NikR family. (139 aa)    
Predicted Functional Partners:
AJF07143.1
MazF family transcriptional regulator; Toxic component of a type II toxin-antitoxin (TA) system.
  
 
 0.821
AJF07557.1
Growth inhibitor PemK; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.821
AJF07667.1
Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.821
AJF05701.1
Cobalamin biosynthesis protein CbiM; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.584
AJF05700.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.502
birA
biotin--acetyl-CoA carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.
     
 0.466
AJF05704.1
Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.450
AJF05703.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.424
Your Current Organism:
Geoalkalibacter subterraneus
NCBI taxonomy Id: 483547
Other names: DSM 23483, G. subterraneus, Geoalkalibacter subterraneus Greene et al. 2009, JCM 15104, KCTC 5626, strain Red1
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