Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
lysADiaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (417 aa)    
Predicted Functional Partners:
AJF07187.1
Aspartate kinase; Catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP, in Bacillus, lysine sensitive; regulated by response to starvation; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aspartokinase family.
  
 0.973
dapF
Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan.
 
 0.962
dapA
Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
  
 0.951
murE
Hypothetical protein; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily.
     
 0.935
dapB
Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family.
 
   
 0.888
AJF07868.1
KamA family protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.800
AJF05868.1
Lysine 2,3-aminomutase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.800
AJF06195.1
Lysine 2,3-aminomutase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.800
AJF06399.1
Lysine 2,3-aminomutase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.800
argH
Argininosuccinate lyase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.768
Your Current Organism:
Geoalkalibacter subterraneus
NCBI taxonomy Id: 483547
Other names: DSM 23483, G. subterraneus, Geoalkalibacter subterraneus Greene et al. 2009, JCM 15104, KCTC 5626, strain Red1
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