Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AJF05947.1DNA methylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (951 aa)    
Predicted Functional Partners:
AJF05942.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.960
AJF05943.1
Alkaline phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.960
AJF05949.1
ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.960
AJF05944.1
Helicase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.957
AJF05948.1
Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.910
AJF05946.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.823
AJF05945.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.773
sucC
succinyl-CoA synthetase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
   
    0.501
sucD
succinate--CoA ligase; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
   
    0.501
Your Current Organism:
Geoalkalibacter subterraneus
NCBI taxonomy Id: 483547
Other names: DSM 23483, G. subterraneus, Geoalkalibacter subterraneus Greene et al. 2009, JCM 15104, KCTC 5626, strain Red1
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