STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CDN41377.1Putative hydrolase; Product derived from UniProtKB/Trembl:R6MLZ1. (241 aa)    
Predicted Functional Partners:
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
    
 0.926
guaA
Putative GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP.
    
  0.914
36.1
Deoxycytidylate deaminase; Product derived from UniProtKB/Swiss-Prot:O22000;Gene name derived from UniProtKB/Swiss-Prot:O22000;EC number derived from UniProtKB/Swiss-Prot:O22000.
  
 
  0.911
purA
Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
    
  0.910
pncB
Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family.
   
 
 0.905
CDN44490.1
Deoxyguanosinetriphosphate triphosphohydrolase-like protein 2; Product derived from UniProtKB/Swiss-Prot:Q9KMM3; Belongs to the dGTPase family. Type 2 subfamily.
    
  0.905
purH
Bifunctional purine biosynthesis protein PurH; Product derived from UniProtKB/Swiss-Prot:Q6HPA0;Gene name derived from UniProtKB/Swiss-Prot:Q6HPA0;EC number derived from UniProtKB/Swiss-Prot:Q6HPA0.
    
  0.905
tmk
Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.
    
  0.904
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
  
 
  0.903
adk
Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.
    
  0.902
Your Current Organism:
Paenibacillus sp. P22
NCBI taxonomy Id: 483908
Other names: P. sp. P22
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