| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| TW91_0108 | TW91_0748 | TW91_0108 | TW91_0748 | Inner membrane protein YicO. | Uracil permease. | 0.416 |
| TW91_0108 | miaB | TW91_0108 | TW91_0109 | Inner membrane protein YicO. | tRNA-I(6)A37 thiotransferase enzyme MiaB; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine. | 0.433 |
| TW91_0108 | purD | TW91_0108 | TW91_0678 | Inner membrane protein YicO. | Phosphoribosylamine--glycine ligase; Belongs to the GARS family. | 0.439 |
| TW91_0108 | purE | TW91_0108 | TW91_1317 | Inner membrane protein YicO. | Phosphoribosylaminoimidazole carboxylase, catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). | 0.523 |
| TW91_0108 | purK | TW91_0108 | TW91_0797 | Inner membrane protein YicO. | Phosphoribosylaminoimidazole carboxylase, ATPase subunit; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). | 0.500 |
| TW91_0108 | purL | TW91_0108 | TW91_1341 | Inner membrane protein YicO. | Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. | 0.900 |
| TW91_0108 | purM | TW91_0108 | TW91_0532 | Inner membrane protein YicO. | Phosphoribosylformylglycinamidine cyclo-ligase. | 0.402 |
| TW91_0748 | TW91_0108 | TW91_0748 | TW91_0108 | Uracil permease. | Inner membrane protein YicO. | 0.416 |
| TW91_0748 | purL | TW91_0748 | TW91_1341 | Uracil permease. | Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. | 0.712 |
| miaB | TW91_0108 | TW91_0109 | TW91_0108 | tRNA-I(6)A37 thiotransferase enzyme MiaB; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine. | Inner membrane protein YicO. | 0.433 |
| purD | TW91_0108 | TW91_0678 | TW91_0108 | Phosphoribosylamine--glycine ligase; Belongs to the GARS family. | Inner membrane protein YicO. | 0.439 |
| purD | purE | TW91_0678 | TW91_1317 | Phosphoribosylamine--glycine ligase; Belongs to the GARS family. | Phosphoribosylaminoimidazole carboxylase, catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). | 0.999 |
| purD | purK | TW91_0678 | TW91_0797 | Phosphoribosylamine--glycine ligase; Belongs to the GARS family. | Phosphoribosylaminoimidazole carboxylase, ATPase subunit; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). | 0.956 |
| purD | purL | TW91_0678 | TW91_1341 | Phosphoribosylamine--glycine ligase; Belongs to the GARS family. | Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. | 0.993 |
| purD | purM | TW91_0678 | TW91_0532 | Phosphoribosylamine--glycine ligase; Belongs to the GARS family. | Phosphoribosylformylglycinamidine cyclo-ligase. | 0.998 |
| purE | TW91_0108 | TW91_1317 | TW91_0108 | Phosphoribosylaminoimidazole carboxylase, catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). | Inner membrane protein YicO. | 0.523 |
| purE | purD | TW91_1317 | TW91_0678 | Phosphoribosylaminoimidazole carboxylase, catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). | Phosphoribosylamine--glycine ligase; Belongs to the GARS family. | 0.999 |
| purE | purK | TW91_1317 | TW91_0797 | Phosphoribosylaminoimidazole carboxylase, catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). | Phosphoribosylaminoimidazole carboxylase, ATPase subunit; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). | 0.999 |
| purE | purL | TW91_1317 | TW91_1341 | Phosphoribosylaminoimidazole carboxylase, catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). | Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. | 0.999 |
| purE | purM | TW91_1317 | TW91_0532 | Phosphoribosylaminoimidazole carboxylase, catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). | Phosphoribosylformylglycinamidine cyclo-ligase. | 0.984 |