| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CoaBC | CoaD | TW91_1800 | TW91_0190 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Pantetheine-phosphate adenylyltransferase. | 0.946 |
| CoaBC | RibD | TW91_1800 | TW91_0407 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.757 |
| CoaBC | RibF | TW91_1800 | TW91_1542 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Riboflavin biosynthesis protein RibF; Belongs to the ribF family. | 0.687 |
| CoaBC | coaE | TW91_1800 | TW91_0971 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | 0.823 |
| CoaBC | coaX | TW91_1800 | TW91_0498 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Bifunctional enzyme BirA/coaX; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. | 0.974 |
| CoaBC | ribB | TW91_1800 | TW91_1386 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | 3,4-dihydroxy-2-butanone-4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. | 0.712 |
| CoaD | CoaBC | TW91_0190 | TW91_1800 | Pantetheine-phosphate adenylyltransferase. | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | 0.946 |
| CoaD | GuaA | TW91_0190 | TW91_1336 | Pantetheine-phosphate adenylyltransferase. | GMP synthase. | 0.604 |
| CoaD | RibD | TW91_0190 | TW91_0407 | Pantetheine-phosphate adenylyltransferase. | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.716 |
| CoaD | RibF | TW91_0190 | TW91_1542 | Pantetheine-phosphate adenylyltransferase. | Riboflavin biosynthesis protein RibF; Belongs to the ribF family. | 0.648 |
| CoaD | TW91_0215 | TW91_0190 | TW91_0215 | Pantetheine-phosphate adenylyltransferase. | RNA methyltransferase, RsmD family. | 0.782 |
| CoaD | coaE | TW91_0190 | TW91_0971 | Pantetheine-phosphate adenylyltransferase. | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | 0.619 |
| CoaD | coaX | TW91_0190 | TW91_0498 | Pantetheine-phosphate adenylyltransferase. | Bifunctional enzyme BirA/coaX; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. | 0.966 |
| CoaD | pheT | TW91_0190 | TW91_1807 | Pantetheine-phosphate adenylyltransferase. | phenylalanyl-tRNA synthetase, beta subunit; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.686 |
| CoaD | ribB | TW91_0190 | TW91_1386 | Pantetheine-phosphate adenylyltransferase. | 3,4-dihydroxy-2-butanone-4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. | 0.651 |
| CoaD | rsmJ | TW91_0190 | TW91_1000 | Pantetheine-phosphate adenylyltransferase. | Hypothetical protein; Specifically methylates the guanosine in position 1516 of 16S rRNA. | 0.608 |
| GuaA | CoaD | TW91_1336 | TW91_0190 | GMP synthase. | Pantetheine-phosphate adenylyltransferase. | 0.604 |
| GuaA | RibD | TW91_1336 | TW91_0407 | GMP synthase. | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.875 |
| GuaA | coaX | TW91_1336 | TW91_0498 | GMP synthase. | Bifunctional enzyme BirA/coaX; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. | 0.478 |
| GuaA | pheT | TW91_1336 | TW91_1807 | GMP synthase. | phenylalanyl-tRNA synthetase, beta subunit; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.962 |