WrbA protein (Neisseria flavescens) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

WrbA

NAD(P)H:quinone oxidoreductase, type IV; Belongs to the WrbA family. (201 aa)

Predicted Functional Partners:

ubiE

0.900

TW91_0518

0.625

TW91_0226

0.506

TW91_2043

0.454

TW91_0516

0.439

TW91_0478

0.402

TW91_0519

0.400

Your Current Organism:

Neisseria flavescens

NCBI taxonomy Id: 484
Other names: ATCC 13120, CCUG 17913, CCUG 345, CIP 73.15, DSM 17633, LMG 5297, LMG:5297, NCTC 8263

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
TW91_0226	WrbA	TW91_0226	TW91_0517	LysM domain protein.	NAD(P)H:quinone oxidoreductase, type IV; Belongs to the WrbA family.	0.506
TW91_0478	WrbA	TW91_0478	TW91_0517	Catalase; Belongs to the catalase family.	NAD(P)H:quinone oxidoreductase, type IV; Belongs to the WrbA family.	0.402
TW91_0516	WrbA	TW91_0516	TW91_0517	Outer membrane ferripyoverdine receptor.	NAD(P)H:quinone oxidoreductase, type IV; Belongs to the WrbA family.	0.439
TW91_0518	TW91_0519	TW91_0518	TW91_0519	tRNA-processing ribonuclease BN.	ABC transporter, periplasmic substrate-binding protein.	0.526
TW91_0518	WrbA	TW91_0518	TW91_0517	tRNA-processing ribonuclease BN.	NAD(P)H:quinone oxidoreductase, type IV; Belongs to the WrbA family.	0.625
TW91_0519	TW91_0518	TW91_0519	TW91_0518	ABC transporter, periplasmic substrate-binding protein.	tRNA-processing ribonuclease BN.	0.526
TW91_0519	WrbA	TW91_0519	TW91_0517	ABC transporter, periplasmic substrate-binding protein.	NAD(P)H:quinone oxidoreductase, type IV; Belongs to the WrbA family.	0.400
TW91_2043	WrbA	TW91_2043	TW91_0517	Hypothetical protein.	NAD(P)H:quinone oxidoreductase, type IV; Belongs to the WrbA family.	0.454
WrbA	TW91_0226	TW91_0517	TW91_0226	NAD(P)H:quinone oxidoreductase, type IV; Belongs to the WrbA family.	LysM domain protein.	0.506
WrbA	TW91_0478	TW91_0517	TW91_0478	NAD(P)H:quinone oxidoreductase, type IV; Belongs to the WrbA family.	Catalase; Belongs to the catalase family.	0.402
WrbA	TW91_0516	TW91_0517	TW91_0516	NAD(P)H:quinone oxidoreductase, type IV; Belongs to the WrbA family.	Outer membrane ferripyoverdine receptor.	0.439
WrbA	TW91_0518	TW91_0517	TW91_0518	NAD(P)H:quinone oxidoreductase, type IV; Belongs to the WrbA family.	tRNA-processing ribonuclease BN.	0.625
WrbA	TW91_0519	TW91_0517	TW91_0519	NAD(P)H:quinone oxidoreductase, type IV; Belongs to the WrbA family.	ABC transporter, periplasmic substrate-binding protein.	0.400
WrbA	TW91_2043	TW91_0517	TW91_2043	NAD(P)H:quinone oxidoreductase, type IV; Belongs to the WrbA family.	Hypothetical protein.	0.454
WrbA	ubiE	TW91_0517	TW91_1236	NAD(P)H:quinone oxidoreductase, type IV; Belongs to the WrbA family.	Ubiquinone/menaquinone biosynthesis methyltransferase UbiE; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2).	0.900
ubiE	WrbA	TW91_1236	TW91_0517	Ubiquinone/menaquinone biosynthesis methyltransferase UbiE; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2).	NAD(P)H:quinone oxidoreductase, type IV; Belongs to the WrbA family.	0.900