Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
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Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
thrBHomoserine kinase; Belongs to the pseudomonas-type ThrB family. (305 aa)    
Predicted Functional Partners:
TW91_1215
Threonine synthase.
    
 0.942
TW91_0527
Homoserine dehydrogenase.
 
  
 0.927
metE
5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family.
     
 0.808
TW91_2034
Branched-chain-amino-acid transaminase.
   
 
 0.801
TW91_0240
L-serine ammonia-lyase; Belongs to the iron-sulfur dependent L-serine dehydratase family.
     
  0.800
LuxS
S-ribosylhomocysteinase LuxS; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family.
     
  0.800
CysE
Serine O-acetyltransferase.
     
  0.800
TW91_1291
Cystathionine beta-lyase.
     
  0.800
TW91_1490
O-succinylhomoserine sulfhydrylase.
     
  0.800
MetW
Methionine biosynthesis protein MetW.
  
     0.569
Your Current Organism:
Neisseria flavescens
NCBI taxonomy Id: 484
Other names: ATCC 13120, CCUG 17913, CCUG 345, CIP 73.15, DSM 17633, LMG 5297, LMG:5297, NCTC 8263
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