| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| GlnA | carA | TW91_1052 | TW91_0979 | Glutamine synthetase, type I. | Carbamoyl-phosphate synthase, small subunit; Belongs to the CarA family. | 0.933 |
| GlnA | carB | TW91_1052 | TW91_0976 | Glutamine synthetase, type I. | Carbamoyl-phosphate synthase, large subunit; Belongs to the CarB family. | 0.915 |
| GlnA | glmS | TW91_1052 | TW91_0696 | Glutamine synthetase, type I. | Glutamine-fructose-6-phosphate transaminase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | 0.941 |
| GlnA | purF | TW91_1052 | TW91_1591 | Glutamine synthetase, type I. | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.916 |
| GlnA | purL | TW91_1052 | TW91_1341 | Glutamine synthetase, type I. | Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. | 0.487 |
| carA | GlnA | TW91_0979 | TW91_1052 | Carbamoyl-phosphate synthase, small subunit; Belongs to the CarA family. | Glutamine synthetase, type I. | 0.933 |
| carA | carB | TW91_0979 | TW91_0976 | Carbamoyl-phosphate synthase, small subunit; Belongs to the CarA family. | Carbamoyl-phosphate synthase, large subunit; Belongs to the CarB family. | 0.999 |
| carA | glmS | TW91_0979 | TW91_0696 | Carbamoyl-phosphate synthase, small subunit; Belongs to the CarA family. | Glutamine-fructose-6-phosphate transaminase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | 0.911 |
| carA | purF | TW91_0979 | TW91_1591 | Carbamoyl-phosphate synthase, small subunit; Belongs to the CarA family. | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.953 |
| carA | purL | TW91_0979 | TW91_1341 | Carbamoyl-phosphate synthase, small subunit; Belongs to the CarA family. | Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. | 0.984 |
| carB | GlnA | TW91_0976 | TW91_1052 | Carbamoyl-phosphate synthase, large subunit; Belongs to the CarB family. | Glutamine synthetase, type I. | 0.915 |
| carB | carA | TW91_0976 | TW91_0979 | Carbamoyl-phosphate synthase, large subunit; Belongs to the CarB family. | Carbamoyl-phosphate synthase, small subunit; Belongs to the CarA family. | 0.999 |
| carB | glmS | TW91_0976 | TW91_0696 | Carbamoyl-phosphate synthase, large subunit; Belongs to the CarB family. | Glutamine-fructose-6-phosphate transaminase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | 0.937 |
| carB | purF | TW91_0976 | TW91_1591 | Carbamoyl-phosphate synthase, large subunit; Belongs to the CarB family. | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.963 |
| carB | purL | TW91_0976 | TW91_1341 | Carbamoyl-phosphate synthase, large subunit; Belongs to the CarB family. | Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. | 0.697 |
| dapE | glmS | TW91_1717 | TW91_0696 | Succinyl-diaminopimelate desuccinylase; Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls; Belongs to the peptidase M20A family. DapE subfamily. | Glutamine-fructose-6-phosphate transaminase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | 0.858 |
| glmM | glmS | TW91_0913 | TW91_0696 | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | Glutamine-fructose-6-phosphate transaminase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | 0.989 |
| glmM | glmU | TW91_0913 | TW91_0697 | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. | 0.993 |
| glmS | GlnA | TW91_0696 | TW91_1052 | Glutamine-fructose-6-phosphate transaminase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | Glutamine synthetase, type I. | 0.941 |
| glmS | carA | TW91_0696 | TW91_0979 | Glutamine-fructose-6-phosphate transaminase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | Carbamoyl-phosphate synthase, small subunit; Belongs to the CarA family. | 0.911 |