Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
HpnDSqualene synthase HpnD. (282 aa)    
Predicted Functional Partners:
TW91_0898
Squalene-associated FAD-dependent desaturase.
    0.960
TW91_0671
Geranyltranstransferase; Belongs to the FPP/GGPP synthase family.
  
 0.917
TW91_0614
Undecaprenyl pyrophosphate synthetase 1; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
   
 
 0.880
IspB
Octaprenyl-diphosphate synthase; Belongs to the FPP/GGPP synthase family.
  
 0.879
HpnC
Squalene synthase HpnC.
 
  
0.705
TW91_0899
Short chain dehydrogenase.
  
 
 0.674
TW91_1225
Multidrug efflux protein.
   
    0.668
Gap
Glyceraldehyde-3-phosphate dehydrogenase, type I.
   
  
 0.497
Gap-2
Glyceraldehyde-3-phosphate dehydrogenase, type I; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
   
  
 0.497
TW91_0819
Ribosomal protein S1; Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.
   
    0.481
Your Current Organism:
Neisseria flavescens
NCBI taxonomy Id: 484
Other names: ATCC 13120, CCUG 17913, CCUG 345, CIP 73.15, DSM 17633, LMG 5297, LMG:5297, NCTC 8263
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.