Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PutABifunctional protein PutA; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. (1201 aa)    
Predicted Functional Partners:
proC
Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
   
 0.973
PutP
Sodium/proline symporter; Catalyzes the sodium-dependent uptake of extracellular L- proline; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
  
  
 0.960
GlnA
Glutamine synthetase, type I.
   
 
 0.957
TW91_1873
NADP-specific glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
  
 
 0.952
TW91_1883
Glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
  
 
 0.952
Pip
Prolyl aminopeptidase; Belongs to the peptidase S33 family.
     
 0.910
TW91_0719
Dihydrolipoyl dehydrogenase.
  
 
 0.908
TW91_0918
Aspartate aminotransferase.
   
 
 0.901
gcvH
Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
    
 0.896
gcvP
Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
   
 
 0.891
Your Current Organism:
Neisseria flavescens
NCBI taxonomy Id: 484
Other names: ATCC 13120, CCUG 17913, CCUG 345, CIP 73.15, DSM 17633, LMG 5297, LMG:5297, NCTC 8263
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.