STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TW91_1029TonB protein; Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins. Belongs to the TonB family. (296 aa)    
Predicted Functional Partners:
TW91_1031
Biopolymer transport protein ExbD.
 
 
 0.985
TW91_1030
Transporter, MotA/TolQ/ExbB proton channel family.
 
 
 0.976
TW91_1196
TonB dependent outer membrane siderophore receptor protein.
 
 
 0.802
TW91_0936
Hemoglobin-haptoglobin utilization protein B.
 
 
 0.738
TW91_1672
Transferrin-binding protein A.
 
 
 0.680
TW91_0003
Transferrin-binding protein A.
 
 
 0.639
TW91_0481
Fe-regulated protein B.
 
 
 0.625
macB
Macrolide export ATP-binding/permease protein MacB; Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.
 
  
 0.567
TW91_1230
TonB-dependent receptor protein.
  
 
 0.554
TW91_1994
TonB-dependent receptor.
  
 
 0.540
Your Current Organism:
Neisseria flavescens
NCBI taxonomy Id: 484
Other names: ATCC 13120, CCUG 17913, CCUG 345, CIP 73.15, DSM 17633, LMG 5297, LMG:5297, NCTC 8263
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