Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Score
TW91_1029TonB protein; Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins. Belongs to the TonB family. (296 aa)    
Predicted Functional Partners:
TW91_1031
Biopolymer transport protein ExbD.
 
 
 0.987
TW91_1030
Transporter, MotA/TolQ/ExbB proton channel family.
 
 
 0.969
TW91_1196
TonB dependent outer membrane siderophore receptor protein.
 
 
 0.890
TW91_1672
Transferrin-binding protein A.
 
 
 0.768
TW91_0936
Hemoglobin-haptoglobin utilization protein B.
 
 
 0.760
TW91_0003
Transferrin-binding protein A.
 
 
 0.739
TW91_0481
Fe-regulated protein B.
 
 
 0.728
TW91_0152
Vulnibactin outer membrane receptor.
  
 
 0.665
TW91_1414
Outer membrane substrate binding protein.
  
 
 0.665
TW91_1415
Outer membrane substrate binding protein.
  
 
 0.665
Your Current Organism:
Neisseria flavescens
NCBI taxonomy Id: 484
Other names: ATCC 13120, CCUG 17913, CCUG 345, CIP 73.15, DSM 17633, LMG 5297, LMG:5297, NCTC 8263
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