| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AdhE | nadD | TW91_0302 | TW91_1084 | Aldehyde-alcohol dehydrogenase 2. | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.478 |
| AdhE | pncB | TW91_0302 | TW91_1049 | Aldehyde-alcohol dehydrogenase 2. | Nicotinate phosphoribosyltransferase; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family. | 0.477 |
| NadC | RibD | TW91_0958 | TW91_0407 | Nicotinate-nucleotide diphosphorylase (carboxylating); Belongs to the NadC/ModD family. | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.543 |
| NadC | TW91_0693 | TW91_0958 | TW91_0693 | Nicotinate-nucleotide diphosphorylase (carboxylating); Belongs to the NadC/ModD family. | Competence/damage-inducible protein CinA domain protein; Belongs to the CinA family. | 0.907 |
| NadC | nadD | TW91_0958 | TW91_1084 | Nicotinate-nucleotide diphosphorylase (carboxylating); Belongs to the NadC/ModD family. | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.911 |
| NadC | pncB | TW91_0958 | TW91_1049 | Nicotinate-nucleotide diphosphorylase (carboxylating); Belongs to the NadC/ModD family. | Nicotinate phosphoribosyltransferase; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family. | 0.928 |
| NadC | surE | TW91_0958 | TW91_1305 | Nicotinate-nucleotide diphosphorylase (carboxylating); Belongs to the NadC/ModD family. | 5'/3'-nucleotidase SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.900 |
| NadE | RibD | TW91_1634 | TW91_0407 | NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source. | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.729 |
| NadE | TW91_0685 | TW91_1634 | TW91_0685 | NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source. | Nicotinamidase. | 0.557 |
| NadE | nadD | TW91_1634 | TW91_1084 | NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source. | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.937 |
| NadE | pncB | TW91_1634 | TW91_1049 | NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source. | Nicotinate phosphoribosyltransferase; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family. | 0.546 |
| RibD | NadC | TW91_0407 | TW91_0958 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Nicotinate-nucleotide diphosphorylase (carboxylating); Belongs to the NadC/ModD family. | 0.543 |
| RibD | NadE | TW91_0407 | TW91_1634 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source. | 0.729 |
| RibD | nadD | TW91_0407 | TW91_1084 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.791 |
| RibD | pncB | TW91_0407 | TW91_1049 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Nicotinate phosphoribosyltransferase; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family. | 0.632 |
| TW91_0685 | NadE | TW91_0685 | TW91_1634 | Nicotinamidase. | NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source. | 0.557 |
| TW91_0685 | pncB | TW91_0685 | TW91_1049 | Nicotinamidase. | Nicotinate phosphoribosyltransferase; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family. | 0.971 |
| TW91_0693 | NadC | TW91_0693 | TW91_0958 | Competence/damage-inducible protein CinA domain protein; Belongs to the CinA family. | Nicotinate-nucleotide diphosphorylase (carboxylating); Belongs to the NadC/ModD family. | 0.907 |
| TW91_0693 | nadD | TW91_0693 | TW91_1084 | Competence/damage-inducible protein CinA domain protein; Belongs to the CinA family. | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.956 |
| TW91_0693 | pncB | TW91_0693 | TW91_1049 | Competence/damage-inducible protein CinA domain protein; Belongs to the CinA family. | Nicotinate phosphoribosyltransferase; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family. | 0.920 |