Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
TW91_1211uroporphyrinogen-III synthase. (327 aa)    
Predicted Functional Partners:
TW91_1210
HemY protein.
  
 0.976
TW91_1212
uroporphyrinogen-III synthase.
  
 0.884
TW91_1853
Tetratricopeptide repeat-containing domain protein.
  
     0.671
recO
DNA repair protein RecO; Involved in DNA repair and RecF pathway recombination.
  
     0.624
TW91_1213
ferredoxin--NADP reductase.
       0.579
lapB
N-acetylglucosaminyl transferase; Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane; Belongs to the LapB family.
  
     0.558
LolB
Outer membrane lipoprotein LolB; Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein.
  
     0.549
TW91_0191
Putative membrane protein; Belongs to the BI1 family.
  
     0.530
IspE
4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase.
  
     0.505
hemE
Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
     
 0.503
Your Current Organism:
Neisseria flavescens
NCBI taxonomy Id: 484
Other names: ATCC 13120, CCUG 17913, CCUG 345, CIP 73.15, DSM 17633, LMG 5297, LMG:5297, NCTC 8263
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