Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TW91_1223TetR-family transcriptional regulator. (216 aa)    
Predicted Functional Partners:
murB
UDP-N-acetylmuramate dehydrogenase; Cell wall formation.
 
     0.660
TW91_1396
Hypothetical protein.
  
     0.617
TW91_1320
Hypothetical protein.
  
     0.564
TW91_1222
NAD-dependent epimerase/dehydratase.
       0.542
TW91_1318
Periplasmic protein.
  
     0.532
TW91_1710
Hypothetical protein.
  
     0.496
macB
Macrolide export ATP-binding/permease protein MacB; Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.
   
 
 0.483
TW91_1766
Gram-negative porin.
  
    0.479
TW91_1221
Hypothetical protein.
       0.443
purL
Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.
      
 0.442
Your Current Organism:
Neisseria flavescens
NCBI taxonomy Id: 484
Other names: ATCC 13120, CCUG 17913, CCUG 345, CIP 73.15, DSM 17633, LMG 5297, LMG:5297, NCTC 8263
Server load: low (14%) [HD]