Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
Gene Fusion
Co-occurrence
Co-expression
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[Homology]
Score
PflBFormate acetyltransferase. (761 aa)    
Predicted Functional Partners:
PflA
Pyruvate formate-lyase 1-activating enzyme.
  
 0.985
AdhE
Aldehyde-alcohol dehydrogenase 2.
 
 
 0.980
TW91_1556
NADP-dependent malic enzyme.
   
 
 0.953
TW91_0719
Dihydrolipoyl dehydrogenase.
   
 
 0.941
Pyk
Pyruvate kinase; Belongs to the pyruvate kinase family.
   
 
 0.931
TW91_1907
Phosphate acetyltransferase.
   
 
 0.912
PpsA
Pyruvate, water dikinase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family.
    
 0.910
AceF
Dihydrolipoyllysine-residue acetyltransferase E2 component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
   
 
 0.909
AldA
Aldehyde dehydrogenase A; Belongs to the aldehyde dehydrogenase family.
  
 
 0.907
TW91_1288
L-lactate dehydrogenase (cytochrome).
     
 0.904
Your Current Organism:
Neisseria flavescens
NCBI taxonomy Id: 484
Other names: ATCC 13120, CCUG 17913, CCUG 345, CIP 73.15, DSM 17633, LMG 5297, LMG:5297, NCTC 8263
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