TypA protein (Neisseria flavescens) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

TypA

GTP-binding protein TypA/BipA. (603 aa)

Predicted Functional Partners:

polA

0.595

rimP

0.538

ychF

0.528

msrA

0.528

rpsI

0.524

GuaA

0.511

TW91_1337

0.511

TW91_1338

0.511

rpmI

0.496

rplA

0.482

Your Current Organism:

Neisseria flavescens

NCBI taxonomy Id: 484
Other names: ATCC 13120, CCUG 17913, CCUG 345, CIP 73.15, DSM 17633, LMG 5297, LMG:5297, NCTC 8263

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
GuaA	TW91_1337	TW91_1336	TW91_1337	GMP synthase.	GMP synthase.	0.995
GuaA	TW91_1338	TW91_1336	TW91_1338	GMP synthase.	GMP synthase.	0.995
GuaA	TypA	TW91_1336	TW91_1310	GMP synthase.	GTP-binding protein TypA/BipA.	0.511
GuaA	polA	TW91_1336	TW91_0167	GMP synthase.	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.	0.839
GuaA	rplA	TW91_1336	TW91_0778	GMP synthase.	Ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.	0.865
GuaA	rpsI	TW91_1336	TW91_0428	GMP synthase.	Ribosomal protein S9; Belongs to the universal ribosomal protein uS9 family.	0.540
GuaA	ychF	TW91_1336	TW91_0082	GMP synthase.	GTP-binding protein YchF; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.	0.454
TW91_1337	GuaA	TW91_1337	TW91_1336	GMP synthase.	GMP synthase.	0.995
TW91_1337	TW91_1338	TW91_1337	TW91_1338	GMP synthase.	GMP synthase.	0.995
TW91_1337	TypA	TW91_1337	TW91_1310	GMP synthase.	GTP-binding protein TypA/BipA.	0.511
TW91_1337	polA	TW91_1337	TW91_0167	GMP synthase.	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.	0.839
TW91_1337	rplA	TW91_1337	TW91_0778	GMP synthase.	Ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.	0.865
TW91_1337	rpsI	TW91_1337	TW91_0428	GMP synthase.	Ribosomal protein S9; Belongs to the universal ribosomal protein uS9 family.	0.540
TW91_1337	ychF	TW91_1337	TW91_0082	GMP synthase.	GTP-binding protein YchF; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.	0.454
TW91_1338	GuaA	TW91_1338	TW91_1336	GMP synthase.	GMP synthase.	0.995
TW91_1338	TW91_1337	TW91_1338	TW91_1337	GMP synthase.	GMP synthase.	0.995
TW91_1338	TypA	TW91_1338	TW91_1310	GMP synthase.	GTP-binding protein TypA/BipA.	0.511
TW91_1338	polA	TW91_1338	TW91_0167	GMP synthase.	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.	0.839
TW91_1338	rplA	TW91_1338	TW91_0778	GMP synthase.	Ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.	0.865
TW91_1338	rpsI	TW91_1338	TW91_0428	GMP synthase.	Ribosomal protein S9; Belongs to the universal ribosomal protein uS9 family.	0.540