Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
TW91_1435Bifunctional protein RfaE, domain I. (320 aa)    
Predicted Functional Partners:
TW91_0499
Bifunctional protein RfaE, domain II.
   
 0.980
GmhB
D,D-heptose 1,7-bisphosphate phosphatase.
 
  
 0.978
gmhA
Phosphoheptose isomerase; Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
 
  
 0.977
hldD
ADP-glyceromanno-heptose 6-epimerase; Catalyzes the interconversion between ADP-D-glycero-beta-D- manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose; Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily.
 
  
 0.910
WaaF
Lipopolysaccharide heptosyltransferase II.
 
   
 0.797
RfaQ
Putative lipopolysaccharide heptosyltransferase III.
 
   
 0.786
pyrF
Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily.
       0.676
WaaC
Lipopolysaccharide heptosyltransferase I.
 
   
 0.652
TW91_1434
NAD-dependent epimerase/dehydratase.
       0.636
TW91_0984
Sugar isomerase, KpsF/GutQ family; Belongs to the SIS family. GutQ/KpsF subfamily.
     
 0.521
Your Current Organism:
Neisseria flavescens
NCBI taxonomy Id: 484
Other names: ATCC 13120, CCUG 17913, CCUG 345, CIP 73.15, DSM 17633, LMG 5297, LMG:5297, NCTC 8263
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