Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TW91_1694Phosphomethylpyrimidine kinase. (200 aa)    
Predicted Functional Partners:
TW91_1685
Phosphatidate cytidylyltransferase.
 
    0.915
TW91_1688
Dual specificity protein phosphatase.
 
   0.823
TW91_1689
Hydrolase, alpha/beta fold family.
 
    0.823
TW91_1686
Phospholipid/glycerol acyltransferase.
 
 
 0.804
TW91_0812
Hypothetical protein.
 
    0.753
TW91_1284
Hypothetical protein.
  
     0.637
TW91_0938
Protein tyrosine/serine phosphatase.
 
  
 0.578
TW91_1370
Phospholipase, patatin family.
 
     0.551
TW91_0766
Integral membrane protein.
  
     0.533
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
     
 0.511
Your Current Organism:
Neisseria flavescens
NCBI taxonomy Id: 484
Other names: ATCC 13120, CCUG 17913, CCUG 345, CIP 73.15, DSM 17633, LMG 5297, LMG:5297, NCTC 8263
Server load: low (40%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.