| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| RpoA | TW91_0773 | TW91_0044 | TW91_0773 | DNA-directed RNA polymerase, alpha subunit. | DNA-directed RNA polymerase, beta' subunit. | 0.985 |
| RpoA | TW91_1323 | TW91_0044 | TW91_1323 | DNA-directed RNA polymerase, alpha subunit. | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. | 0.488 |
| RpoA | groL | TW91_0044 | TW91_0479 | DNA-directed RNA polymerase, alpha subunit. | Chaperonin GroL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.521 |
| RpoA | rpoB | TW91_0044 | TW91_0775 | DNA-directed RNA polymerase, alpha subunit. | DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.999 |
| RpoA | rpoC | TW91_0044 | TW91_0772 | DNA-directed RNA polymerase, alpha subunit. | DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.989 |
| RpoA | rpoH | TW91_0044 | TW91_1787 | DNA-directed RNA polymerase, alpha subunit. | Alternative sigma factor RpoH; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes. | 0.924 |
| RpoA | rpoZ | TW91_0044 | TW91_1888 | DNA-directed RNA polymerase, alpha subunit. | DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. | 0.999 |
| RpoA | topA | TW91_0044 | TW91_0216 | DNA-directed RNA polymerase, alpha subunit. | DNA topoisomerase; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA superc [...] | 0.894 |
| TW91_0773 | RpoA | TW91_0773 | TW91_0044 | DNA-directed RNA polymerase, beta' subunit. | DNA-directed RNA polymerase, alpha subunit. | 0.985 |
| TW91_0773 | rpoB | TW91_0773 | TW91_0775 | DNA-directed RNA polymerase, beta' subunit. | DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.999 |
| TW91_0773 | rpoC | TW91_0773 | TW91_0772 | DNA-directed RNA polymerase, beta' subunit. | DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.994 |
| TW91_0773 | rpoH | TW91_0773 | TW91_1787 | DNA-directed RNA polymerase, beta' subunit. | Alternative sigma factor RpoH; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes. | 0.700 |
| TW91_0773 | rpoZ | TW91_0773 | TW91_1888 | DNA-directed RNA polymerase, beta' subunit. | DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. | 0.910 |
| TW91_0773 | topA | TW91_0773 | TW91_0216 | DNA-directed RNA polymerase, beta' subunit. | DNA topoisomerase; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA superc [...] | 0.758 |
| TW91_1323 | RpoA | TW91_1323 | TW91_0044 | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. | DNA-directed RNA polymerase, alpha subunit. | 0.488 |
| TW91_1323 | msrA | TW91_1323 | TW91_0673 | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. | Peptide methionine sulfoxide reductase MsrA/msrB; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. | 0.702 |
| TW91_1323 | rpoB | TW91_1323 | TW91_0775 | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. | DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.468 |
| TW91_1323 | rpoH | TW91_1323 | TW91_1787 | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. | Alternative sigma factor RpoH; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes. | 0.656 |
| TW91_1323 | topA | TW91_1323 | TW91_0216 | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. | DNA topoisomerase; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA superc [...] | 0.764 |
| dnaJ | groL | TW91_0304 | TW91_0479 | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | Chaperonin GroL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.958 |