Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AdhPAlcohol dehydrogenase, propanol-preferring. (342 aa)    
Predicted Functional Partners:
AdhE
Aldehyde-alcohol dehydrogenase 2.
 
 0.995
TW91_1859
Aldehyde dehydrogenase family protein; Belongs to the aldehyde dehydrogenase family.
  
 0.942
TW91_1973
Zinc-binding alcohol dehydrogenase.
 
 
 0.759
TW91_1556
NADP-dependent malic enzyme.
  
  
 0.655
leuC
3-isopropylmalate dehydratase, large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.
    
 
 0.625
TW91_1173
S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.
  
 
 
 0.555
PheA
P-protein.
      
 0.460
TW91_1909
Alcohol dehydrogenase, zinc-containing.
 
 
0.449
TW91_1248
AMP-binding enzyme.
  
  
 0.421
TW91_0719
Dihydrolipoyl dehydrogenase.
   
 
 0.415
Your Current Organism:
Neisseria flavescens
NCBI taxonomy Id: 484
Other names: ATCC 13120, CCUG 17913, CCUG 345, CIP 73.15, DSM 17633, LMG 5297, LMG:5297, NCTC 8263
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