TW91_1910 protein (Neisseria flavescens) - STRING interaction network

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TW91_1910

A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. (322 aa)

Predicted Functional Partners:

TW91_0248

0.824

Xth

0.742

Xth-2

0.742

msrA

0.679

polA

0.642

metG

0.506

TW91_1909

0.480

mutL

0.432

recX

0.423

radA

0.422

Your Current Organism:

Neisseria flavescens

NCBI taxonomy Id: 484
Other names: ATCC 13120, CCUG 17913, CCUG 345, CIP 73.15, DSM 17633, LMG 5297, LMG:5297, NCTC 8263

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
TW91_0248	TW91_1910	TW91_0248	TW91_1910	DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs.	0.824
TW91_0248	Xth	TW91_0248	TW91_0521	DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	Exodeoxyribonuclease III.	0.795
TW91_0248	Xth-2	TW91_0248	TW91_1124	DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	Exodeoxyribonuclease III.	0.795
TW91_0248	metG	TW91_0248	TW91_0663	DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	methionine--tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.	0.481
TW91_0248	mutL	TW91_0248	TW91_0795	DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.	0.984
TW91_0248	polA	TW91_0248	TW91_0167	DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.	0.996
TW91_1909	TW91_1910	TW91_1909	TW91_1910	Alcohol dehydrogenase, zinc-containing.	A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs.	0.480
TW91_1910	TW91_0248	TW91_1910	TW91_0248	A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs.	DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	0.824
TW91_1910	TW91_1909	TW91_1910	TW91_1909	A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs.	Alcohol dehydrogenase, zinc-containing.	0.480
TW91_1910	Xth	TW91_1910	TW91_0521	A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs.	Exodeoxyribonuclease III.	0.742
TW91_1910	Xth-2	TW91_1910	TW91_1124	A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs.	Exodeoxyribonuclease III.	0.742
TW91_1910	metG	TW91_1910	TW91_0663	A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs.	methionine--tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.	0.506
TW91_1910	msrA	TW91_1910	TW91_0673	A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs.	Peptide methionine sulfoxide reductase MsrA/msrB; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.	0.679
TW91_1910	mutL	TW91_1910	TW91_0795	A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs.	DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.	0.432
TW91_1910	polA	TW91_1910	TW91_0167	A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs.	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.	0.642
TW91_1910	radA	TW91_1910	TW91_1525	A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs.	DNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.	0.422
TW91_1910	recX	TW91_1910	TW91_1885	A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs.	Regulatory protein RecX; Modulates RecA activity; Belongs to the RecX family.	0.423
Xth	TW91_0248	TW91_0521	TW91_0248	Exodeoxyribonuclease III.	DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	0.795
Xth	TW91_1910	TW91_0521	TW91_1910	Exodeoxyribonuclease III.	A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs.	0.742
Xth	Xth-2	TW91_0521	TW91_1124	Exodeoxyribonuclease III.	Exodeoxyribonuclease III.	0.925