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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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experimentally determined
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TW91_2008Succinate dehydrogenase iron-sulfur subunit; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. (235 aa)    
Predicted Functional Partners:
SdhA
Succinate dehydrogenase, flavoprotein subunit; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
 
 0.999
SdhD
Succinate dehydrogenase, hydrophobic membrane anchor protein.
 
 0.999
SdhC
Succinate dehydrogenase, cytochrome b556 subunit.
 
 0.999
TW91_1159
Fumarate hydratase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
  
 
 0.994
sucD
succinate-CoA ligase, alpha subunit family; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
 
 0.990
sucC
succinyl-CoA synthetase beta chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
 
 0.985
TW91_0719
Dihydrolipoyl dehydrogenase.
  
 
 0.973
NuoE
NADH dehydrogenase [ubiquinone] flavoprotein 2, precursor.
   
 
 0.966
fumC
Fumarate hydratase, class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
  
 0.962
PetA
Ubiquinol-cytochrome c reductase, iron-sulfur subunit; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
  
 
 0.956
Your Current Organism:
Neisseria flavescens
NCBI taxonomy Id: 484
Other names: ATCC 13120, CCUG 17913, CCUG 345, CIP 73.15, DSM 17633, LMG 5297, LMG:5297, NCTC 8263
Server load: low (16%) [HD]
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