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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
TW91_2034Branched-chain-amino-acid transaminase. (317 aa)    
Predicted Functional Partners:
leuA
2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
  
 0.987
ilvD
Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family.
  
 0.966
PanB
3-methyl-2-oxobutanoate hydroxymethyltransferase.
     
 0.916
ilvA
Threonine ammonia-lyase, biosynthetic; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
  
 0.915
TW91_1628
Aminotransferase AlaT.
  
 
 0.913
TW91_1291
Cystathionine beta-lyase.
   
 0.909
TW91_0487
Valine--pyruvate aminotransferase.
     
 0.904
GshA
Glutamate--cysteine ligase.
   
 
  0.900
TW91_0527
Homoserine dehydrogenase.
  
 
 0.847
thrB
Homoserine kinase; Belongs to the pseudomonas-type ThrB family.
   
 
 0.801
Your Current Organism:
Neisseria flavescens
NCBI taxonomy Id: 484
Other names: ATCC 13120, CCUG 17913, CCUG 345, CIP 73.15, DSM 17633, LMG 5297, LMG:5297, NCTC 8263
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