Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
THA_255Iron (III) ABC transporter, permease protein; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily. (325 aa)    
Predicted Functional Partners:
THA_254
Iron (III) ABC transporter, periplasmic-binding.
 
 
 0.992
THA_1650
Hemin transport system ATP-binding protein HmuV.
 
 
 0.980
THA_1807
Conserved hypothetical protein.
  
 
 0.909
THA_256
NagD protein; Belongs to the HAD-like hydrolase superfamily.
       0.751
THA_257
RNA polymerase sigma-H factor; Belongs to the sigma-70 factor family.
  
  
 0.743
THA_1078
Uroporphyrinogen III synthase/methyltransferase; Belongs to the precorrin methyltransferase family.
  
  
 0.598
THA_248
Isochorismatase-related protein.
  
  
 0.494
ribB
A 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family. In the N-terminal section; belongs to the DHBP synthase family.
     
 0.485
THA_252
Thiamine pyrophosphokinase.
       0.440
dxr
1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family.
       0.440
Your Current Organism:
Thermosipho africanus
NCBI taxonomy Id: 484019
Other names: T. africanus TCF52B, Thermosipho africanus TCF52B, Thermosipho africanus str. TCF52B, Thermosipho africanus strain TCF52B
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