Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
THA_362Conserved hypothetical protein. (791 aa)    
Predicted Functional Partners:
THA_363
Conserved hypothetical protein.
       0.824
THA_364
1-acyl-sn-glycerol-3-phosphate acetyltransferase; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
     
 0.824
thiI
Thiamine biosynthesis/tRNA modification protein ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
       0.821
THA_361
Membrane protein, putative.
       0.807
THA_359
ABC transporter, ATP-binding protein.
  
    0.791
THA_360
Hypothetical protein.
       0.789
THA_358
Protein UshA; Belongs to the 5'-nucleotidase family.
       0.686
THA_366
Iron permease FTR1 family.
       0.504
msrA
Peptide methionine sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
    
   0.455
Your Current Organism:
Thermosipho africanus
NCBI taxonomy Id: 484019
Other names: T. africanus TCF52B, Thermosipho africanus TCF52B, Thermosipho africanus str. TCF52B, Thermosipho africanus strain TCF52B
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