Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
thrBSerine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the pseudomonas-type ThrB family. (325 aa)    
Predicted Functional Partners:
AJR24446.1
Homoserine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.930
AJR24347.1
Threonine synthase; Catalyzes the formation of L-threonine from O-phospho-L-homoserine; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.919
ispH
4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family.
       0.860
rnhA
Ribonuclease HI; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
       0.860
AJR22934.1
Catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.811
AJR26352.1
Cystathionine beta-lyase; Catalyzes the formation of L-homocysteine from cystathionine; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.811
metZ
O-succinylhomoserine sulfhydrylase; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide.
     
 0.809
AJR23540.1
O-acetylhomoserine aminocarboxypropyltransferase; Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
  0.806
ahcY
S-adenosyl-L-homocysteine hydrolase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
    
  0.805
AJR22661.1
5-methyltetrahydrofolate--homocysteine methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
  0.804
Your Current Organism:
Sphingobium sp. YBL2
NCBI taxonomy Id: 484429
Other names: S. sp. YBL2
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