| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AJR22672.1 | AJR25723.1 | TZ53_01590 | TZ53_20235 | Bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Riboflavin biosynthesis protein RibF; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ribF family. | 0.733 |
| AJR22672.1 | coaD | TZ53_01590 | TZ53_03075 | Bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.959 |
| AJR22672.1 | coaE | TZ53_01590 | TZ53_04530 | Bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | 0.608 |
| AJR22672.1 | coaX | TZ53_01590 | TZ53_20510 | Bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Pantothenate kinase; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. | 0.939 |
| AJR22672.1 | guaA | TZ53_01590 | TZ53_10820 | Bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.452 |
| AJR22898.1 | AJR22900.1 | TZ53_03070 | TZ53_03080 | Peptidylprolyl isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. | Farnesyl-diphosphate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the FPP/GGPP synthase family. | 0.730 |
| AJR22898.1 | coaD | TZ53_03070 | TZ53_03075 | Peptidylprolyl isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.715 |
| AJR22898.1 | queA | TZ53_03070 | TZ53_03065 | Peptidylprolyl isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. | S-adenosylmethionine tRNA ribosyltransferase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). | 0.701 |
| AJR22898.1 | xseB | TZ53_03070 | TZ53_03085 | Peptidylprolyl isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. | Exodeoxyribonuclease VII small subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family. | 0.744 |
| AJR22900.1 | AJR22898.1 | TZ53_03080 | TZ53_03070 | Farnesyl-diphosphate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the FPP/GGPP synthase family. | Peptidylprolyl isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. | 0.730 |
| AJR22900.1 | coaD | TZ53_03080 | TZ53_03075 | Farnesyl-diphosphate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the FPP/GGPP synthase family. | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.902 |
| AJR22900.1 | guaA | TZ53_03080 | TZ53_10820 | Farnesyl-diphosphate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the FPP/GGPP synthase family. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.471 |
| AJR22900.1 | queA | TZ53_03080 | TZ53_03065 | Farnesyl-diphosphate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the FPP/GGPP synthase family. | S-adenosylmethionine tRNA ribosyltransferase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). | 0.712 |
| AJR22900.1 | xseB | TZ53_03080 | TZ53_03085 | Farnesyl-diphosphate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the FPP/GGPP synthase family. | Exodeoxyribonuclease VII small subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family. | 0.918 |
| AJR25237.1 | coaD | TZ53_17380 | TZ53_03075 | Methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.837 |
| AJR25723.1 | AJR22672.1 | TZ53_20235 | TZ53_01590 | Riboflavin biosynthesis protein RibF; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ribF family. | Bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | 0.733 |
| AJR25723.1 | coaD | TZ53_20235 | TZ53_03075 | Riboflavin biosynthesis protein RibF; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ribF family. | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.754 |
| AJR25723.1 | coaE | TZ53_20235 | TZ53_04530 | Riboflavin biosynthesis protein RibF; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ribF family. | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | 0.660 |
| AJR25723.1 | guaA | TZ53_20235 | TZ53_10820 | Riboflavin biosynthesis protein RibF; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ribF family. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.456 |
| coaD | AJR22672.1 | TZ53_03075 | TZ53_01590 | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | Bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | 0.959 |