Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
AJR23046.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (396 aa)    
Predicted Functional Partners:
AJR23045.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.522
guaB
Inosine-5-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
   
 0.502
AJR23149.1
Ankyrin; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.498
AJR26044.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.498
ispDF
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D- erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C- methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF).
     
 0.469
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
   
 0.466
AJR24151.1
Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  0.461
AJR24152.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  0.461
AJR23684.1
2-acyl-glycerophospho-ethanolamine acyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.436
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
    
 0.431
Your Current Organism:
Sphingobium sp. YBL2
NCBI taxonomy Id: 484429
Other names: S. sp. YBL2
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